Wimbledon 2022 LIVE: Andy Murray vs John Isner result and updates as Brit suffers second-round defeat

Wimbledon 2022 - LIVE!

John Isner has had plenty of time to ponder how to beat Andy Murray. At his ninth time of asking, he finally cracked it.

That Isner had never beaten Murray before was something of a mystery with the manner of his victory. He was far more than the 6ft 10in serving machine that he is often portrayed, although there were still 36 aces.

He hit a total of 82 winners – more than double that of his opponent – and at times showed a delightful deftness of touch as Murray failed to make the third round of Wimbledon for the first time in his career in a 6-4, 7-6, 6-7, 6-4 defeat.

Having got himself back to his best form since hip surgery three-and-a-half years ago, it would be premature to call time on his Wimbledon career at 35. After all, Isner is two years older and played some of his best tennis in his only third ever appearance on Centre Court.

But this was a painful evening for Murray, and the earliest Wimbledon exit of his career.

Murray vs Isner latest news

• Isner secures 6-4 7-6 6-7 6-4 win

• Murray takes match to a fourth set

• Isner moves two sets up after tie-break

• Isner takes first set on Centre Court

Murray’s run over

21:42 , Matt Verri

John Isner has had plenty of time to ponder how to beat Andy Murray. At his ninth time of asking, he finally cracked it.

That Isner had never beaten Murray before was something of a mystery with the manner of his victory. He was far more than the 6ft 10in serving machine that he is often portrayed, although there were still 36 aces.

He hit a total of 82 winners – more than double that of his opponent – and at times showed a delightful deftness of touch as Murray failed to make the third round of Wimbledon for the first time in his career in a 6-4, 7-6, 6-7, 6-4 defeat.

Having got himself back to his best form since hip surgery three-and-a-half years ago, it would be premature to call time on his Wimbledon career at 35. After all, Isner is two years older and played some of his best tennis in his only third ever appearance on Centre Court.

In Murray’s second such appearance in just the space of 48 hours, he remonstrated with himself, shaking his head with increasing frustration and also berating his box at shots he would have made in his prime.

Read Matt Majendie’s full report

More from Isner

21:31 , Matt Verri

“I am most definitely not a better tennis player than Andy Murray, I was just a little bit better than him today.”

21:29 , Matt Verri

How did you hold your nerve when Murray threatened a comeback, Isner is asked.

“I served,” is the dry response.

He’s not wrong!

Murray 4-6 6-7 7-6 4-6 Isner

21:23 , Matt Verri

Murray up of his chair, Centre Court rises in response. Now or never.

Big cheers as Isner nets the first serve, less so when Murray’s forehand off the second serve flies long. 15-0. Ace. 30-0. And another ace. 40-0. Three match points Isner. Been an unbelievable performance on serve from the American.

GAME, SET, MATCH. Andy Murray is out of Wimbledon.

Murray 4-6 6-7 7-6 4-5* Isner

21:19 , Matt Verri

Murray serving to stay in the tournament.

He gets to an Isner drop shot, tries to flick it crosscourt but finds the net. First serve out wide, Isner’s return lands long. 15-15. This one’s wide, 30-15.

Lovely drop shot, Isner doesn’t even try and chase it down. Double fault from Murray follows though, 40-30.

American frames that return, flies long and Murray holds. Has to break next game or it’s all over.

Murray 4-6 6-7 7-6 *3-5 Isner

21:15 , Matt Verri

A quarter of the way to a break - 0-15! Murray is able to get into a rally, Isner sends the backhand into the net.

Make that halfway to a break, stunning backhand pass from Murray! Absolutely perfect, it’s 0-30.

That kills the mood, huge ace. 15-30. Murray goes to his right, ace goes to the left. 30-30. Three in a row! 40-30, outrageous from Isner.

Murray gets the second serve back, but Isner puts away the forehand. He’s one game away from victory.

Murray 4-6 6-7 7-6 3-4* Isner

21:10 , Matt Verri

Open the roof! Poor backhand from Murray, halfway up the net.

Big first serve is the response, Isner barely gets a racket on it. 15-15. Followed up with an ace, before he moves in really nicely and puts the volley away. 40-15.

First serve again and there’s a hold for Murray. Now the hard work starts.

Here we go...

21:07 , Matt Verri

Lights are on, Murray ready to serve.

Can he somehow send this to a fifth set?

21:05 , Matt Verri

Murray will serve when play gets back underway very soon.

He’ll need to hold, and then hope to find a solution to the problem that Isner’s serve continues to pose.

Roof will be closed!

20:59 , Matt Verri

Murray gets his wish, despite Isner already getting ready for the next game.

The roof will be shut and the lights turned on. Play paused for about ten minutes on Centre Court, Murray will be hoping it slows the Isner serve machine.

Murray 4-6 6-7 7-6 *2-4 Isner

20:58 , Matt Verri

Murray asks the question as he lobs the ball up, confident answer from Isner who puts it away. Backs it up with a huge ace out wide, 30-0. Those two unforced errors in the last game looking more and more painful by the second.

Keeps the slice low, Isner can’t get down to it. 30-15. Chalk flies up, signals another Isner ace. Murray tells the umpire it’s too dark - it is very gloomy. Break in play to close the roof would suit the Brit.

Lovely backhand crosscourt, Isner can’t make the volley. 40-30.

Murray does everything possible to stay in the point, return on the stretch and then a good backhand. Isner up to the task and he holds.

Murray 4-6 6-7 7-6 2-3* Isner

20:52 , Matt Verri

Forehand shovelled towards the baseline from Isner, called out by the Centre Court crowd but line calls are beyond their jurisdiction. Drop shot from Murray is good enough to win the point anyway.

He tries it again but Isner is ready this time and puts away the forehand. 30-15. That’s long from Murray, 30-30. Bit of pressure on his serve now.

Twice backhands hammered at Isner, who moves up to the net. Murray tries the pass instead... long. Break point Isner! Saved! Backhand delivers this time for Murray, Isner sent sprawling as he tries to get down for the volley. Deuce, as Murray pumps up the crowd once more.

Break point again! Massive mistake from Murray. Ball sits up for him but he slams the backhand straight into the net.

Taken! Murray nets again and Isner has an absolutely massive break.

Murray 4-6 6-7 7-6 *2-2 Isner

20:45 , Matt Verri

Isner volley at the net flies wide, but he quickly backs it up with another ace. That’s 31 for the match for the American.

Second serve for Murray to ‘attack’ - it’s still 116mph. Backhand into the net. 40-15. Great from Murray, big backhand down the line sets up a simple enough volley at the net. 40-30.

Massive second serve from Isner, the Brit can’t get it back and we’re level again in the fourth.

Murray 4-6 6-7 7-6 2-1* Isner

20:40 , Matt Verri

Isner gets a taste of his own medicine, as Murray powers down an ace out wide. And another ace, this one 126mph. 40-0.

Murray puts absolutely no effort into the drop shot, it slides just over the net and that’s a breezy hold.

Murray 4-6 6-7 7-6 *1-1 Isner

20:38 , Matt Verri

Momentum with Murray, can he find a first break of the Isner serve?

That helps, unforced error from the American. Two in a row in fact, 15-30. Picture brightening somewhat for Murray.

Someone turned the lights off again. Two aces later, it’s 40-30. The second in after a challenge from Isner, found about a millimetre of the line.

Good forehand from Isner and that’s a hold, though he had to work a bit harder for it.

Murray 4-6 6-7 7-6 1-0* Isner

20:34 , Matt Verri

Isner furious with himself as a he sends a backhand rolling into the net. Been a fair few from the American that have been a long way from the middle of the racket.

That’s a bit closer, still out though. 30-15. Big serve out wide, Isner can’t get it back.

And there’s the hold. Punishing rally, Isner blinks first.

Murray to serve first in fourth set

20:31 , Matt Verri

Murray 4-6 6-7 7-6 Isner

20:27 , Matt Verri

SET MURRAY!

He’s skipping around in celebration long before the Isner shank comes back down to earth.

GAME. ON.

20:26 , Matt Verri

Groans from Centre Crowd as Murray’s first serve finds the net. High standards. Absolutely huge celebrations from the Brit as Isner nets the second-serve return. That was a big point, he leads 5-2 now.

Return from Murray is good, Isner’s volley bending down somehow finds it’s way over the net. Brilliant touch. 5-3 Murray.

6-3 Murray! That’s huge! Backhand crosscourt is good enough, Isner can’t make the volley and it’s two set points. Both on Murray’s serve.

20:23 , Matt Verri

Mini-break for Murray! Absolutely huge. Gets the first serve back, and it’s a really tight forehand from Isner. Sails long.

Murray’s box on their feet again, as their man sends a lovely slice dropping over the net. 2-0. Isner shanks a second-serve return. 3-0 Murray. Bit of a free hit at the two Isner serves to come.

Serve and volley from the American is too good, 3-1. Murray goes early, guesses correctly but the first serve is still too good. Ace. 3-2.

Forehand whipped from Murray, Isner can’t get it back in play. 4-2 Murray at the changeover.

Murray 4-6 6-7 6-6 Isner

20:19 , Matt Verri

Back to Murray serving to stay in the tournament.

Positive start, big first serve and Isner’s return sails long. As it does next point, Murray quickly 30-0 up.

SHOT! Sensational drop shot from Murray - Isner saw it coming a mile off and still couldn’t get there. 40-0. And there’s the hold.

We’re going to another tie-break!

Murray 4-6 6-7 *5-6 Isner

20:15 , Matt Verri

Cheers of anticipation as Murray gets an Isner serve back, the American finds a forehand winner though. 30-0.

That’s straight off the frame from Isner though, a bit of hope for Murray. Perhaps not, serve and volley is good from the American and it’s 40-15.

Another superb Isner volley, another Isner hold.

Murray 4-6 6-7 5-5* Isner

20:12 , Matt Verri

Here we go then, Murray’s tournament on the line. Isner’s sliced return into the net, 15-0. Make that 30-0, drop shot from Murray isn’t the best but it’s a brilliant forehand pass to get the job done instead.

Isner mishits a return into the net, before he shanks another backhand. Hold to love.

Now - can Murray finally do something on the Isner serve?

Murray 4-6 6-7 *4-5 Isner

20:09 , Matt Verri

Almost a perfect return from Murray, lands just wide. Decides not to challenge. The Brit then bounces his racket as another ace comes flying down. 30-0.

He can only watch again, 134mph ace. 40-0. Isner goes for a massive second serve, double fault. Probably a risk worth taking.

Especially when Isner then puts away the volley for another routine hold. Murray will serve to stay in the match.

Murray 4-6 6-7 4-4* Isner

20:06 , Matt Verri

Huge game - Murray gets broken here and Isner will be serving for the match.

Good start, Murray comes forward and it’s a lovely volley at the net. Net cord briefly causes Murray some problems next point, but he adjusts well. 30-0. Monstrous return from Isner keeps him in in touch.

American nets it this time though, 40-15. Backhand from Isner looks to be sailing long, lands right on the line. Murray doesn’t get anywhere near enough on the lob, 40-30.

This one is long. Murray holds!

Murray 4-6 6-7 *3-4 Isner

20:01 , Matt Verri

Massive cheers as Isner nets a first serve. That is very much the stage we are now out.

Murray does well to keep himself in the point, launches the ball high but Isner is up to the task. Puts it away, 30-0. Nothing the Brit can do there, 130mph ace. 40-0. Crowd trying their best to get behind their man but this serving from Isner is ridiculous.

Another ace to add to the tally, comfortable hold.

Murray 4-6 6-7 3-3* Isner

19:59 , Matt Verri

Pretty much a situation now where Murray cannot afford to be broken.

Not a great start on that quest, Isner hammers a second-serve return just inside the baseline. He’s in trouble next point, but saves himself with a sensational backhand pass. Massive fist pump to go with it, Centre Court reacts. 15-15.

Terrible slice from Isner, bounces before it even gets to the net. Massive backhand from the American, Murray manages to get it back and Isner then frames the forehand long. 40-15.

And there’s the hold, a huge one too! He turns his attention to firing up the crowd.

Murray 4-6 6-7 *2-3 Isner

19:54 , Matt Verri

Murray looking up at his box, unsure what he’s supposed to do as he’s unable to lay a racket on two Isner serves. 30-0.

He at least has a couple of shots in the next point, but he’s never really in the point and Isner puts away the overhead at the net.

The pattern continues - when Murray gets into a rally, he’s completely in control. Isner backhand floats long. 40-15. Two Isner second serves flick off the top of the net. Gets the job done with his third ‘second’ serve.

Murray 4-6 6-7 2-2* Isner

19:51 , Matt Verri

Isner guesses early on the Murray second serve, not sure there’s any need. Especially when you guess incorrectly. 15-0.

First serve out wide from the Brit, Isner can’t get that back either. Good serve, good forehand, Isner getting a taste of his own medicine. 40-0.

Big serving again and that’s a rapid hold to love.

Murray 4-6 6-7 *1-2 Isner

19:47 , Matt Verri

Two first serves from Isner and he doesn’t need to hit another shot. 30-0 - Murray can’t find a way to even get into a rally on the Isner serve.

This time the Brit does force Isner into a longer exchange, and the American responds with an unforced error. And again - 40-30. Glimmer of hope for Murray?

No. 132mph ace out wide. Brutal.

Murray 4-6 6-7 1-1* Isner

19:44 , Matt Verri

Isner slice into the net, couple of unforced errors from the American to start the game.

Is that a second serve ace? It is indeed! 40-0. No sign of any underarm serves from Murray so far this evening.

Isner extends the game with a nice volley, and Murray then slaps a forehand into the net. 40-30. There’s the hold though, relief for the Brit.

Murray 4-6 6-7 *0-1 Isner

19:41 , Matt Verri

Isner serving first in the set isn’t great for Murray either, way the American is bombing them down he’s always going to be under pressure.

That’s flicked long from Isner though, 40-30. Any hope that the door was slightly open ends with Isner sending down another ace.

Murray 4-6 6-7 Isner

19:36 , Matt Verri

Two set points Isner, as Murray slices the return into the net. 6-4.

Isner takes the second set! Serve does the job for the American and he is a set away from knocking Murray out of Wimbledon.

19:35 , Matt Verri

Chance was there for Murray to get it back on serve. Isner did really well to stoop down and get the volley back, Murray has the opening for a backhand pass. Into the net, 5-2 Isner. Two Murray serves to come.

Isner lob doesn’t have enough on it, easily put away by Murray. 5-3. First serve out wide, Isner can’t return. 5-4 - Murray still in touch. Has to win at least one of these next two points on the Isner serve though.

19:32 , Matt Verri

Not the start Murray needed, Isner steps forward and takes control. He’s got the mini-break early on, that could be all he needs the way he’s serving.

Ace Isner, 2-0. Back on serve now though! Murray’s able to get into a rally and Isner produces an unforced error. 2-1 Isner.

Mini-break for the American once more, balls sits up to be hit and the Isner forehand delivers for him this time. First serve keeps Murray in touch, 3-2 Isner.

Serve and volley from Isner is good, he leads 4-2 at the changeover.

Murray 4-6 6-6 Isner

19:28 , Matt Verri

One particular line judge is having a miserable time out there. Right in the firing line when Isner’s at the opposite end, three times she’s almost ended up on the floor.

Murray gets to the serve in plenty of time, slice is long though. Really frustrated with himself. 30-15.

Back in play, Isner forehand lets him down again. Maybe not - challenge from the American, a good one too. Found the line. 40-15.

Massive ace and we’re going to a tie-break!

Murray 4-6 6-5* Isner

19:24 , Matt Verri

Drop volley is so good from Isner, Murray almost takes the net with him as he charges after it. Can’t get there.

Second serve for Isner to attack, he tries but completely frames it into the ground. 15-15. Slice from Murray, making Isner bend down and it’s a good tactic. Isner can only find the net.

Forehand put away from Murray, 40-15, before Isner’s slice is a poor one.

Isner up to try and take it to a tie-break.

Murray 4-6 *5-5 Isner

19:20 , Matt Verri

Can Murray put some pressure on the serve of Isner? Good start, backhand from Isner flies long. 0-15.

The Brit then does really well to run down a drop shot, can’t do anything more than float it straight at Isner though and it’s a simple volley into an entirely empty court.

Isner getting a bit edgy when Murray returns the first serve. Sliced back to the American and the forehand is wild once again. 15-30. That’s brilliant though, ball drops at his feet at the net and he just lifts it over.

Murray screams at the umpire to get his attention, wants to challenge as an Isner volley drops very close to the line. Might have been better had the umpire not heard - it’s in. Isner levels the set up.

Murray 4-6 5-4* Isner

19:14 , Matt Verri

Long rally, which is always going to favour Murray. He keeps the slice low and Isner can’t get under the forehand. 30-0.

Again it’s a length exchange, ended by Murray with a perfect drop shot. Isner didn’t move. American jumps all over the second serve though, huge return. 40-15.

Serve out wide, Isner on the stretch can’t do anything with it. Isner will serve to stay in the second set.

Murray 4-6 *4-4 Isner

19:11 , Matt Verri

Isner serve is doing a decent job of flattening the Centre Court atmosphere. Seems to produce an ace whenever the crowd start to get involved again.

Forehand has misfired on a number of occasions for the American and does so again, 15-15.

Stunning return, 15-30. Crowd really up now. Cheers as Murray gets a 138mph serve back in play, pass is there for him... can’t make it. Head in his hands. 30-30.

Isner serve called out, challenge from the American. Comfortably out. Does the job with the second serve instead.

Murray return rolls into the net, game Isner.

Murray 4-6 4-3* Isner

19:06 , Matt Verri

Vintage Murray backhand, flattens it out crosscourt and Isner can only watch it past him.

The Brit sets up the point with a big forehand, can’t put it away at the net though. 15-30. First serve right when he needed it, ‘come on’ from Murray before the return had even landed out.

Fist pump this time, as Isner nets the return. Murray knows he can’t afford to be broken here. 40-30.

Brilliant backhand winner and that’s an important hold.

Murray 4-6 *3-3 Isner

19:01 , Matt Verri

Murray getting a cheer every time he even gets an Isner serve back in play. Manages to reach the overhead too, but the volley at the net from the American is too good. 30-0.

That’s straight into the net from Isner though. Quickly back on track with a massive ace out wide. And again. Level once more in the second set.

Murray 4-6 3-2* Isner

18:57 , Matt Verri

Good serving from Murray in response to that dominant Isner hold. A couple of serves don’t come back and he’s swiftly 40-0 to the good.

Brit sends a slice wide, but gets the job done with a 122mph ace.

Murray 4-6 *2-2 Isner

18:54 , Matt Verri

Just as the cries of ‘come on Andy’ die down, Isner starts the game with an ace out wide.

Two first serves later and it’s 40-0, the American hasn’t had to hit a second shot in a point yet.

And he won’t have to - another ace and it’s a hold to love. Brutal serving.

Murray 4-6 2-1* Isner

18:51 , Matt Verri

Too good from Isner, hammers a second-serve return just inside the baseline. Yell of frustration from Murray.

And now a double fault from the Brit, 0-30. As we saw in the first set, you can’t afford to let Isner get a break up.

‘Come on’ says Murray as a first serve gets the job done, before he very nearly throws in another double. Turns out to be perfect and Isner can’t get the return in. 30-30.

Ace from Murray, challenged by Isner. It’s caught the smallest possible piece of the line! No challenge for that one, ace out wide and murray has reeled off four points in a row to get an important hold.

Murray 4-6 *1-1 Isner

18:48 , Matt Verri

Ace out wide from Isner sounded like a gunshot, 130mph. He goes wide again, Murray this time only able to frame it into the crowd.

The Brit at last is able to get one in play, and the response from Isner is a truly wild forehand. Job done though with yet another ace.

Murray 4-6 1-0* Isner

18:45 , Matt Verri

Nice backhand down the line from Murray to start the set, finishes off the point with a forehand at the net.

Again the backhand does the damage, this time there’s no need for a follow-up from the Brit. 40-0.

Isner slices into the net, but Murray has challenged the shot earlier that he thinks was out. It was in - if Murray had kept quiet he’d have won the game! Drop shot into the net from Murray, 40-30.

There’s the hold though, no more self-inflicted drama for Murray.

Murray 4-6 Isner

18:39 , Matt Verri

Line judge sent diving for cover as Isner takes aim with another massive serve. Groan from Murray as he gets one back in play, almost took his wrist off. Lands just inside the baseline, Isner with a superb overhead. 30-15.

Ace from the American brings up two set points.

Murray dumps a backhand into the net and Isner has taken the first set 6-4 on Centre Court!

Murray 4-5* Isner

18:35 , Matt Verri

Murray reads the latest Isner drop shot and gets there to flick it down the line. Lovely shot.

Forehand winner followed by an ace, Murray races to 40-0. Another ace for a hold - Isner challenges though. He was unsure whether he could be bothered at 40-0 down. Good decision though, it was out.

Wonderful pass down the line from Isner, 40-15. Maybe he’s not done with this game yet...

He very much is. Return into the net and Murray does his job. Over to Isner to serve for the set.

Murray *3-5 Isner

18:32 , Matt Verri

We’re seeing some lovely touch from Isner to go with the massive serving. Two perfect drop shots get him 30-0 up.

There’s the power, forehand whipped crosscourt and it’s a clean winner, before Murray pulls it return out. Isner breezes through another service game.

Murray will serve to extend the first set.

Murray 3-4* Isner

18:28 , Matt Verri

Massive return from Isner, right at the feet of Murray and he can’t do much with it. 15-30, the American sensing another opportunity on the Murray serve.

Should be 15-40 - relatively simple smash at the net from Isner, sends it long. Murray let off the hook.

Ace from the Brit come at a very welcome time, but Isner comes forward again and has all the time in the world to just drop the ball over the net. Deuce.

Beuatiful slice from Murray is good enough to be a winner, before Isner goes for a slice of his own. Rolls into the net.

Murray *2-4 Isner

18:23 , Matt Verri

Isner has an age to wait for the ball to drop, as Murray launches it up into the sky. Not hugely convincing from the American, but Murray can’t find the pass down the line.

137mph serve right at Murray’s body, he puts a racket up in self-defence as much as anything else. Flies long. Hold to love.

Murray 2-3* Isner

18:20 , Matt Verri

Stunning from Murray! Lob from Isner is great, but the Brit chases it down and on the spin fires a backhand winner down the line. So, so good.

Isner then sends two returns comfortably out and Murray has a swift hold to love.

Murray *1-3 Isner

18:18 , Matt Verri

Backhand crosscourt from Isner is too good, Murray can only watch it drop in as it flies past him.

Isner then nets a forehand though, as Murray gets another huge serve back in play. 15-30. Serve and volley is quite effective when the serve is that good. 30-30.

SHOT! Backhand crosscourt from Murray, Isner moving forward can’t intercept. Fist pump to the crowd, break point Murray. Saved. Murray reads the smash, gets it back but it’s a lovely volley from Isner at the net. Deuce.

Can’t pull off the volley this time though, another break point coming up for Murray. Door slammed shut, ace.

And again. Murray then at least gets a racket on the serve, but the return flies long. Isner comes through the test.

Murray 1-2* Isner

18:11 , Matt Verri

Anything you can do... Murray sends down an ace of his own, before getting the drop shot all wrong again. 15-30, slight sniff for Isner.

More than that now, as Murray goes for the backhand pass down the line and finds the net. Two break point points Isner.

Isner breaks! Comes forward, nice backhand and Murray has lost serve very early on. Isner really isn’t the man to fall a break behind to...

Murray *1-1 Isner

18:07 , Matt Verri

132mph first serve pounded down from Isner, Murray gets it back in play and Isner sends the forehand long. The Brit won’t be laying a racket on that though, ace out wide. You can expect more of those. A lot more. 30-15.

Massive second serve this time, Isner needs a couple of attempts at the overhead to get the point won.

Murray makes a bit of a mess of an attempted drop shot and that’s an Isner hold.

Murray 1-0* Isner

18:03 , Matt Verri

Umpires absolutely screams ‘let’ as Murray’s serve clips the net. Someone is very excited to be here. Mammoth rally to kick things off, which Isner gets the better of. Not sure he’ll be keen for too many rallies with almost 20 shots in though.

Another long rally, Murray goes down the line with a backhand and Isner can’t get it back.

Routine hold from Murray to kick things off.

Warm-ups done!

17:58 , Matt Verri

Few rallies, a couple volleys and smashes and then some serves to finish up. Both players back to their chairs ahead of this one getting underway.

Another one of these this evening?

17:54 , Matt Verri

17:52 , Matt Verri

Isner ducks as he walks out, to a slightly muted response. Big cheers as Murray follows behind.

Centre Court only about half full, following the Raducanu match. Sure it will quickly fill up again before too long.

17:46 , Matt Verri

Murray next up on Centre Court, after that Raducanu defeat.

No pressure Andy, but we could really do with some good news for the Brits today...

Emma Raducanu is OUT

17:39 , Marc Mayo

A straight-sets defeat for the British youngster on Centre Court before this clash...

Prediction

17:32 , Marc Mayo

After making a bit of a meal of his first-round match, Isner has plenty to prove in what will be a fiery Centre Court, charged by the earlier matches involving two big names.

It is hard to see the Murray resurgence going too deep into the tournament but he surely has the ability to down a player even longer in the tooth than he is.

Murray to win in four sets.

How to watch

17:26 , Marc Mayo

TV channel: The BBC will broadcast the match on BBC One. When the match takes place between 6pm and 7pm, coverage will switch to BBC Two.

Live stream: TV licence fee-payers can stream the tennis action over the next two weeks via the BBC iPlayer, BBC Sport website and app.

Welcome to Murray vs Isner LIVE coverage!

15:33 , Marc Mayo

Hello and welcome to Standard Sport’s latest LIVE coverage from Wimbledon.

Andy Murray is the focus of attention on Centre Court once again tonight as he looks to reach the third round following Monday’s rousing comeback win over James Duckworth.

Standing in the two-time champion’s way is John Isner, the big-serving American who has lost all eight of his previous meetings against this evening’s opponent.

Murray is third on Centre on day three, so expect the match to start in the aftermath of Emma Raducanu’s clash with Caroline Garcia.

Follow all the action live with Matt Verri at the All England Club.