London Stadium welcomes the side that finished seventh in last season’s Danish Superliga for the first of a two-legged play-off to determine who will reach the group stages.
Declan Rice will miss both legs after being slapped with a two-game ban for his comments against the referee following the Hammers’ Europa League semi-final defeat.
Aaron Cresswell was sent off in that game and serves a one-game ban, leaving a question mark as to who will captain West Ham in his and Rice’s absence.
Likewise, David Moyes serves a one-game touchline suspension for kicking out at a ball boy in his team’s defeat in Germany late last season.
Assistant coach Billy McKinlay confirmed on Wednesday that new signing Thilo Kehrer could feature in the squad.
He told reporters: “We’ll see how [Thilo] settles in, get a bit of feedback from him and see how he feels over the next 24 hours. He trained a little bit with us this morning.”
Maxwel Cornet and Gianluca Scamacca make their first starts but there is no space in the XI for Flynn Downes.
Craig Dawson is nearing his return from a leg muscle injury but Nayef Aguerd (ankle) is out and there is a return from a long-term knee injury for Angelo Ogbonna.
West Ham XI: Areola; Coufal, Ogbonna, Johnson, Ashby; Soucek, Coventry; Bowen, Lanzini, Cornet; Scamacca.
Subs: Trott, Randolph, Zouma, Kehrer, Baptiste, Chesters, Ekwah, Fornals, Downes, Okoflex, Benrahma, Antonio.