The No. 5 USC Trojans are back on the field this week and heading on the road to Arizona State to continue Pac-12 conference play. This matchup offers star quarterback Caleb Williams a good tune up ahead of the team's road showdown with Colorado Sept. 30.
This will be the 40th and last time USC and Arizona State face off as Pac-12 members. Next year, USC's heading to the Big 10 while Arizona State is set to join the Big 12.
This is the first road game of the year for the Trojans, who've hosted San Jose State, Nevada, and Stanford. All three were wins by a combined score of 178-52. Arizona State is 1-2 in head coach Kenny Dillingham's first season at the helm. Last week, the Sun Devils notched the first home shutout in 35 years with a 29-0 loss to Fresno State. With that recent loss, the Trojans are heavily favored to take their fourth straight win.
How to watch No. 5 USC vs. Arizona State: TV and streaming
Arizona State will be hosting No. 5 USC with kickoff set for 10:30 p.m. ET. It will be broadcast live on Fox and streamed on the FoxSports App.
Notable football players and injury news:
USC defensive lineman Tyrone Taleni is probable
Arizona State quarterback Drew Pyne is probable
Arizona State running back DeCarlos Brooks is questionable
Arizona State tight end Jalin Conyers is questionable
Arizona State quarterback Jaden Rashada is out
Arizona State quarterback Trenton Bourguet is doubtful
Arizona State defensive end Clayton Smith is doubtful
Arizona State wide receiver Jordyn Tyson is out
Arizona State offensive lineman Isaia Glass is questionable
Arizona State running back George Hart III is questionable
Last year, Arizona State kept this game close through the first half before USC took over to win 42-25. Williams completed 27 of 37 passes for 348 yards and four total touchdowns (three passing, one rushing). With a different group of weapons this season, he'll look to replicate his success and maintain the top spot in the latest Heisman trophy odds.
On the other side, quarterback Drew Pyne makes his first start for Arizona State after transferring from Notre Dame. Pyne came in last week against Fresno State after injuries to starter Jaden Rashada and backup Trenton Bourguet. Pyne went 8-2 as a starter last year for the Irish and had 318 yards and three touchdowns in Notre Dame's 38-27 loss to the Trojans.
NCAA Odds Week 4: No. 5 USC vs. Arizona State lines, betting trends:
Point Spread: USC -34.5
Moneyline: USC -10000 / Arizona State +3000
USC Trojans remaining schedule and results:
Week 0: USC 56-28 San Jose State Final
Week 1: USC 66-14 Nevada Final
Week 2: USC 56-35 Colorado State Final
Week 3: Bye
Week 4: Sat. Sept. 23: USC-Arizona State, 10:30 p.m., ET, FOX
Week 5: Sat. Sept. 30: USC-Colorado, 12:00 p.m., ET, FOX
Week 6: Sat. Oct. 7: USC-Arizona, TBD
Week 7: Sat. Oct. 14: USC-Notre Dame, time TBD, NBC/Peacock
Week 8: Sat. Oct. 21: USC-Utah, TBD
Week 9: Sat. Oct. 28: USC-California, TBD
Week 10: Sat. Nov. 4: USC-Washington, TBD
Week 11: Sat. Nov. 11: USC-Oregon, TBD
Week 12: Sat. Nov. 18: USC-UCLA, TBD
Conference showdown: 5 ways Deion Sanders' Colorado team can shock Oregon and move to 4-0
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This article originally appeared on USA TODAY: Injury updates, betting info, and how to watch USC take on ASU