Steven Psihogios and Wesley Cheng count you down to the final week of the fantasy season, and make the case for Jalen Hurts, Cole Beasley, Leonard Fournette and Logan Thomas as league winners.
Steven Psihogios and Wesley Cheng count you down to the final week of the fantasy season, and make the case for Jalen Hurts, Cole Beasley, Leonard Fournette and Logan Thomas as league winners.
Police say the woman fled after hitting the 53-year-old man on northbound Brookshire Boulevard.
Past social media posts included liking comments about hanging Barack Obama, shooting Nancy Pelosi, and executing FBI agents
McCarthy plans to have conversation with Ms Greene about ‘deeply disturbing’ comments
Paramount is moving its animated feature Rumble from May 14 this year to Feb. 18, 2022. The movie directed by Hamish Grieve is set in the world of monster wrestling where monsters are superstar athletes. Teenage Winnie seeks to follow in her father’s footsteps by coaching a loveable underdog monster into a champion. Matt Lieberman and Etan […]
Money is weird.
HAIFA, Israel, Jan. 27, 2021 /CNW/ -- ZIM Integrated Shipping Services Ltd.
Former minister reportedly suggested official Covid figures have been ‘manipulated’
Carey Mulligan explains why she publicly called out a "Variety" review for her film "Promising Young Woman" – and received an apology.
A motorist accused of hitting pedestrians, bicyclists and killing a 77-year-old woman Monday in Portland, Oregon, has pleaded not guilty to murder and has given detectives bizarre explanations about the incident, according to court documents. Paul Rivas, 64, through a court-appointed lawyer, also pleaded not guilty Wednesday to six counts of second-degree assault, six counts of failure to perform the duties of a driver after causing injuries, and one count of failure to perform the duties of a driver resulting in a death. Prosecutor Sean P. Hughey wrote in a probable cause affidavit that Rivas initially told investigators his Honda Element was having brake problems and that he was searching for an auto repair shop.
According to IDC, smartphone vendors shipped a total of 385.9 million devices in Q3 2020, an increase of 4.3% over the same quarter in 2019.
Queer Catholic advocates have welcomed bishops’ call to protect LGBTQ youth. But they say they need actions, too.
At the Jan. 18 Limerick Township council meeting, Victoria Tisdale, clerk and treasurer, gave her clerk’s report to council, in which she welcomed new deputy clerk and treasurer Nicole Ilcio, gave an update on outstanding tax collection, and an update on some outstanding administrative and financial issues. She also provided council with her Community Emergency Management Coordinator report, detailing the current lockdown and stay-at-home order and the restrictions the township was following to adhere to them. Tisdale began her report by welcoming the township’s newest employee, the new deputy clerk and treasurer Nicole Ilcio. She had Ilcio come over and say hello to the rest of council over the Zoom call, and council instructed Tisdale to mention in the council meeting minutes that they had welcomed and congratulated Ilcio as their new hire. Tisdale also informed council that she had sent out the St. Ola boathouse registration reminder letters, with a copy of the bylaw as well as the boathouse map. According to Tisdale, the township had collected $160,112.62 in outstanding taxes in the period from Nov. 1 to Dec. 31. She also sent out a letter to ratepayers outlining payment options to clear up arrears to avoid the prospect of a tax sale. She also told council that she had been working on the year end close, as well as the draft 2021 budget. Tisdale brought up two additions to her clerk’s report, items that came in after she hadsubmitted the written report. The first was in regard to the outstanding balance of $27,500 from the 2019 Fire Agreement with Tudor and Cashel Township, an amount that Tisdale said had now been paid in full. This paves the way for Limerick to proceed with the Joint Services Fire Agreement that is in the planning stages with Tudor and Cashel Township, Wollaston Township and Madoc Township, without this money issue between Limerick and Tudor and Cashel. The second item was to tell council that they had until Jan. 28 to submit a summer student job grant application. “There’s a couple of stipulations, but we were thinking it would be great to help with some grass cutting or work at the dump on the weekends. With council’s approval, I will go ahead and submit that application,” she says. Council gave Tisdale the go ahead on this application. Tisdale also provided council with her CEMC report, reiterating that a provincial lockdown had been in place since Dec. 26, 2020 and that a state of emergency and stay-at-home order had been issued by the Ontario government on Jan. 12. She said the municipal office had been closed to the public since Dec. 26, 2020, and that staff have been in the building to answer emails and phone calls and run the day-to-day township operations. Masks are required of all employees and council members when they come into the office. She recommended that the next council meeting and planning meeting be done by Zoom to adhere to the regulations and to lead by example for the community. Councillor Jan MacKillican asked if there was some way to have a work at home rotation for the office staff. Tisdale replied that it would be problematic to do that right now while training Ilcio as the new deputy clerk and treasurer. “We really couldn’t do any training if she’s at home. If we have days full of webinars then yes, we’ll stay at home. We’re staying distanced in the building when we are here. I can’t really see any way around getting trained up and keeping on top of things while we’re at home,” she says. MacKillican agreed, and said she had just wanted to float the rotation idea and get Tisdale’s thoughts on it. Mayor Carl Stefanski then asked if there were any further questions for Tisdale, and hearing none, they moved on to other business. Michael Riley, Local Journalism Initiative Reporter, The Bancroft Times
A Calgary woman's love of animals has lead to her creating a miniature farm in her home — leading to two of the animals becoming inseparable. Jody Fraser, who lives just east of Calgary, moved to the countryside last year with her two cats, dog and turtle. And because she now has the space, she decided to get some chickens as well. "So that was the beginning of my fascination with all of the animals," she told the Calgary Eyeopener. All of the animals live under the same roof — except for the chickens — making them pretty close pals. About three months ago, Fraser added a pig to the mix. "He's just the nicest little crazy pig ever and very, very low maintenance," she said. "I've always just loved the pigs. So it's kind of funny how now I have my own." While most get along, two of the species are especially close. Wilbur the pot-bellied pig, who is now five-months-old, has became best buds with a new 12-week kitten named Billy. "The two, just right from the beginning, became the best buddies ever. They just love each other. I'm not sure where it came from," she said. Not only do the two animals sleep with one another, but they also make sure one another is clean. "The pig will clean the kitten, actually, and every once in a while you see the kitten actually cleaning the pig's ears. So it's kind of funny." And because of how close the two are, she is unsure what to do once the pig gets bigger. "I was only going to keep him in the house because he's still really little … but I was to put him outside in the spring," she said. "I'm hoping that I do decide to still do that, but he's become part of the family now, so I don't see him going outside." What is it like having a pet pig? Fraser says not only is Wilbur cleaner than her cats and dog, but he is also house trained. "I have one of those kiddy pools and that's where he has to go," she said. "But he originally started with the kitty litter box, but he was trained like within a day or two." When he is not cuddling with Billy, Wilbur is outside with the chickens or being taken on walks. "We have a little ramp that goes into my little yard where my chickens are and stuff, and he goes and runs and plays with the chickens." Since posting her little animal family updates, Fraser has become popular on Facebook, Instagram and even TikTok. "Every day they do something silly. I have my camera out all the time, so I just post five or six pictures everyday of their craziness." Her pages feature all of the animals of the house, but viewers have come to really love Wilbur and Billy, so the pair may get their own account sometime soon. And by spring you may just see another animal thrown into the mix. "I can't bring any more animals in my house, obviously, because I would, of course." "But I would love to get some goats and a donkey one day too maybe in the springtime for sure." You can follow Wilbur the Pig and Billy the Kitten on Facebook, Instagram or TikTok to see more. Listen to the full interview below: With files from the Calgary Eyeopener.
HOLX earnings call for the period ending December 26, 2020.
Welcome to Accuray's conference call to review financial results for the second quarter of fiscal year 2021, which ended December 31, 2020. Joining us on today's call are Josh Levine, Accuray's President and Chief Executive Officer; Shig Hamamatsu, Accuray's Senior Vice President and Chief Financial Officer; and Suzanne Winter, Accuray's Chief Commercial Officer and Senior Vice President of R&D.
The 2020 tax season is coming. You better start preparing, as two big changes are coming to your tax calculation this year. The post Canada Revenue Agency: 2 Big Changes Coming to Your 2020 Tax Bill appeared first on The Motley Fool Canada.
Starz has promoted Karen Bailey to Executive Vice President of Original Programming, from her previous SVP role. In her expanded position, Bailey will continue to spearhead the network’s inclusion initiatives across the slate with a focus on narratives by, about and for women and underrepresented audiences. She will also continue to expand the drive toward […]
Applications opened up on Jan. 15 for the Ontario Small Business Support Grant. First announced in December, the grant gives eligible small businesses a minimum of $10,000 to a maximum of $20,000 to those who have had to restrict their operations due to the current provincial lockdown, the latter measure put in place to help stop the rise of COVID-19 cases in Ontario. Businesses approved for the grant can expect to get their money within approximately 10 business days. By Jan. 22, the number of applications to his grant had exceeded 42,000. In the press release about the program from Jan. 15, Minister of Finance and President of the Treasury Board Peter Bethlenfalvy, says that Ontario’s employers are facing unprecedented challenges as they do their part to defeat COVID-19. “I encourage every eligible small business owner in Ontario to visit Ontario.ca/COVIDSupport to access the support our government has made available. While we still have a lot of work ahead of us, we can all look confidently to the future as we resolve to do our parts and put COVID-19 behind us,” he said. Small businesses that needed to close or reduce their services under the lockdown can apply for this one time grant and use the funding in whatever way meets their individualbusiness needs. According to the news release, eligible small businesses include; those that have had to close or reduce their operations due to the lockdown that began on Dec. 26, those that have fewer than 100 employees at the enterprise level and those that have experienced a minimum of 20 per cent revenue decline in April 2020 compared to April 2019. Businesses that started up since April 2019 will also be eligible if they meet the other eligibility criteria. Approved businesses can expect payment within approximately 10 business days. Andrew Redden is the economic development manager with Hastings County, and thinks that it is great that the province has come out with this grant to support small businesses. “It’s great to see that there. We’ve been promoting it to as many businesses as possible and our small business coach, Mark Hanley, has been talking to a lot of businesses that have asked for help, even just to navigate their system for applying for the grant,” he says. Redden also mentions a section on the Hastings County website dedicated to COVID-19 business resources that small businesses can access anytime at hastings.ca/resources/resources-for-business-during-COVID-19/. Jody Yantha is the executive officer with the Bancroft Business Improvement Area and says that it is wonderful that the provincial government is providing some support for local business owners who are suffering with this current lockdown. “It is refreshing that the program will support eligible businesses who may use the funds the way they see fit, whatever way makes the most sense for their business. This provides flexibility for individual needs. Some businesses might want to use the funds to pay staff, while others may want to use it to pay rent,” she says. Yantha reveals that the online portal to apply for this grant is streamlined and easy to use, as she sat in on a Zoom meeting hosted by officials from various provincial ministries which included a demonstration of this online portal. Angela Pollak from the South Algonquin Business Association says that grant opportunities are essential to the survival of the tourism industry right now with COVID-19, especially in rural and remote locations like South Algonquin Township. “I’m pleased to see the Ford government recognizing and responding to the need and especially enthusiastic for the operators who are eligible to receive the funds. However, I remain concerned about the large number of operators in our region and regions like ours who are shut out of these opportunities by unnecessary barriers and limits to eligibility. Summer seasonal operators and accommodation providers are currently ineligible and especially at risk right now. We have a situation where the government is saying to some, here is the money to help you survive, while at the same time saying to others, if you want to survive, you’ll need to get a loan,” she says. Pollak says that after a devastating 2020 season and an uncertain 2021, most small tourism operators can’t afford loans. She says if this inequity goes on, the ability of tourism dependent rural and remote regions to bounce back from the financial struggles wrought by the pandemic will be compromised. “I am personally thankful for the work of James Murphy at Explorers Edge/RTO12, Dan Kelly at the Canadian Federation of Independent Businesses and the Tourism Industry Association of Ontario, who know the challenges we face and who are advocating tirelessly on behalf of our businesses right now. In the meantime, buoyed by their support, SABA continues to look to the new year with hope, and to meet the challenges we face with a flexible, creative and innovative frame of mind,” she says. Gary and Lillian Pattison own the Old Hastings Mercantile and Gallery in Ormsby, located in Limerick Township. They said they looked into and filled out the application for the Ontario small business support program. “It wasn’t too complicated, though there were a few bits that were not clear. We did have to phone for some help, and that call went right through very quickly to a real person. Now we’ll wait and see if we qualify and for what in particular,” they said. Emily Hogeveen is the director of issues management and strategic media relations with the Office of the Minister of Finance Peter Bethlenfalvy, and she says that that grant has been generally well received across the province by small businesses, as well as the CFIB and the Ontario Chamber of Commerce. “This new grant is in addition to the property tax and energy relief grant we have previously announced for businesses affected by the pandemic,” she says. By Jan. 22, in an Ontario.ca news release update provided by Bethlenfalvy, Vic Fedelli, Minister of Economic Development, Job Creation and Trade, Prabmeet Sarkaria, Associate Minister of Small Business and Red Tape Reduction and Lisa Thompson, Minister of Government and Consumer Services, the online small business support grant portal had received over 42,000 applications. Michael Riley, Local Journalism Initiative Reporter, The Bancroft Times
With over 30+ players proactively involved in developing novel therapies for Non-Muscle Invasive Bladder Cancer (NMIBC) and over 30+ therapies expected to get launched, Non-Muscle Invasive Bladder Cancer Pipeline presents quite a promising overall picture for the next decade.Los Angeles, USA, Jan. 27, 2021 (GLOBE NEWSWIRE) -- Non-Muscle Invasive Bladder Cancer Pipeline Analysis Shows Tremendous Growth Opportunities for the Coming Years With over 30+ players proactively involved in developing novel therapies for Non-Muscle Invasive Bladder Cancer (NMIBC) and over 30+ therapies expected to get launched, Non-Muscle Invasive Bladder Cancer Pipeline presents quite a promising overall picture for the next decade. “Non-Muscle Invasive Bladder Cancer (NMIBC) Pipeline Insight, 2021” by DelveInsight highlights the details around the NMIBC pipeline scenario, unmet needs, and Non-Muscle Invasive Bladder Cancer therapeutic assessment of the key pipeline therapies. Some of the key Non-Muscle Invasive Bladder Cancer Pipeline Highlights: 30+ key companies including the APIM Therapeutics, UroGen Pharma, Pfizer, AstraZeneca, TARIS Biomedical, Bristol-Myers Squibb, Ono Pharmaceuticals, Janssen Pharmaceuticals, and several others. are involved in adding value to the Non-Muscle Invasive Bladder Cancer pipeline. 30+ emerging therapies are in the NMIBC pipeline at different stages of clinical development including ATX-10, Imfinzi, TAR-200, Sasanlimab, Balversa, UGN-102, Opdivo, and several others.While ATX-101 and TAR-200 are in early stages of clinical development (ATX-101 in preclinical stages and TAR 200 in Phase I); UGN-102, and Balversa are in Phase II stage of trials with Opdivo and PF-06801591 in the end-stage (Phase III) of clinical development.Anchiano Therapeutics is leveraging its expertise in small-molecule oncology development and is developing novel small-molecule inhibitors of RAS and PDE10/β-catenin in collaboration with ADT Pharmaceuticals. LIPAC is working to enhance the therapeutic index of proven cancer drugs, which results in more effective treatments for intracavitary cancers with the help of its proprietary proliposomal intracavitary paclitaxel drug delivery platform, LiPax. LIPAC announced the successful completion of a Phase 2A marker lesion clinical trial designed to predict long-term (two-year) recurrence-free survival rates in patients with low-grade highly recurrent NMIBC treated with LiPax.In August 2020, GeneCentric Therapeutics entered into a research collaboration with Janssen around RNA-based drug response biomarkers for non-muscle invasive bladder cancer. Non-Muscle Invasive Bladder Cancer is a common, heterogeneous cancer found in the tissue of the bladder's inner surface, wherein the bladder muscle is not involved. NMIBC Pipeline Therapies Opdivo: Bristol-Myers Squibb/Ono Pharmaceuticals Opdivo (Nivolumab) is a programmed death-1 (PD-1) immune checkpoint inhibitor developed by Bristol-Myers Squibb. The drug harnesses the body’s immune system to help restore anti-tumor immune response by blocking the interaction between PD-1 and its ligands. Opdivo holds a vital place as the treatment option across multiple cancers. It has been approved for colorectal cancer; gastric cancer; Head and neck cancer; Hodgkin's disease; Liver cancer; Malignant melanoma; Mesothelioma; Non-small cell lung cancer; Renal cell carcinoma; Urogenital cancer, and is currently in phase III clinical development for participants with High-risk Non-muscle Invasive Bladder Cancer that is persistent or recurrent after treatment with BCG in a phase III trial titled “a phase III, randomized, double-blind trial of Nivolumab in combination with Intravesical BCG Versus Standard of Care BCG alone’’ (NCT04149574). The trial is currently in the recruiting stage with an estimated enrollment of 700 participants and expected to be completed in August 2030. BMS is also evaluating Opdivo in a phase II trial titled “a phase II, randomized, open-label study of Nivolumab or Nivolumab/BMS-986205 alone or combined with intravesical BCG in participants with BCG-Unresponsive, high-risk, Non-Muscle Invasive Bladder Cancer” (NCT03519256). The trial is currently in the recruiting stage with an estimated enrollment of 358 participants and expected to be completed in September 2024. UGN-102: UroGen Pharma UGN-102 (mitomycin gel) is an investigational formulation that utilizes innovative technology, RTGel reverse-thermal hydrogel, for the treatment of low-grade NMIBC. UroGen Pharma is investigating the therapy in phase 3, to assess the long-term efficacy and safety of UGN-102 (mitomycin) for an intravesical solution with or without (±) transurethral resection of bladder tumors. The trial is currently in the recruiting stage with an estimated enrolment of 632 participants and expected to be completed in December 2023. Atezolizumab: Hoffmann-La Roche Roche’s Atezolizumab (Tecentriq), a monoclonal antibody designed to bind with a protein called PD-L1 expressed on tumour cells and tumour-infiltrating immune cells, is already commercially available for Breast cancer; Liver cancer; Malignant melanoma; Non-small cell lung cancer; Small cell lung cancer; and Urogenital cancer. Roche is also evaluating the drug for Non-Muscle Invasive Bladder Cancer. It is currently in the recruiting stage with an estimated enrollment of 614 participants and expected to be completed in February 2028. To learn more about NMIBC Drugs Development, request NMIBC Drugs Pipeline Sample Report Scope of Non-Muscle Invasive Bladder Cancer Pipeline Report Coverage: Global Major Players: 30+ companiesProminent Players: Bristol-Myers Squibb, Ono Pharmaceuticals, Pfizer, Merck Sharp & Dohme Corp., Ferring Pharmaceuticals, UroGen Pharma, Roche, Viventia Bio, ImmunityBioKey Drugs: 30+ pipeline drugsNon-Muscle Invasive Bladder Cancer Therapies: Atezolizumab, ALT-803, UGN-102, Vicinium, Nivolumab, Pembrolizumab, PF-06801591, Durvalumab, APL-1202Phases Non-Muscle Invasive Bladder Cancer Therapies Late-stage (Phase III) NMIBC Therapies (Phase II)NMIBC Therapies (Phase I) Non-Muscle Invasive Bladder Cancer Therapies Pre-clinical stage candidates Inactive candidates and Discovery candidates for Non-Muscle Invasive Bladder Cancer Targets ProteaseImmune System Multiple Kinase And others Mechanism of Action Protease Inhibitor Immunomodulatory Multiple Kinase InhibitorAnd others Molecule Types AntineoplasticsVaccineGene therapiesImmunotherapyMetalMonoclonal antibodiesNanoparticleOncolytic virusesPeptidePlasmidProteinSmall moleculeLigandBacteria and others. Route of Administration InfusionIntradermalIntravenousIntravesicalOralAnd others Product Types MonoCombination Mono/Combination Visit to know more about the report offerings @ Non-Muscle Invasive Bladder Cancer Emerging Therapies Key Questions Answered in Non-Muscle Invasive Bladder Cancer Pipeline Report How many companies are developing Non-muscle invasive bladder cancer drugs?How many Non-muscle invasive bladder cancer drugs are developed by each company?How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Non-muscle invasive bladder cancer?What are the key collaborations (Industry–Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Non-muscle invasive bladder cancer therapeutics?What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?What are the clinical studies going on for Non-muscle invasive bladder cancer and their status?What are the key designations that have been granted to emerging drugs? Get in touch with our Business Executive @ NMIBC Pipeline Trends and Futuristic Outlook to learn more about the domain. Table of Contents 1Introduction2Executive Summary3Non-Muscle Invasive Bladder Cancer: Overview4NMIBC Pipeline Therapeutics5Therapeutic Assessment6Non-Muscle Invasive Bladder Cancer – DelveInsight’s Analytical Perspective7In-depth Commercial Assessment8Non-Muscle Invasive Bladder Cancer Collaboration Deals9NMIBC Late-Stage Products10NMIBC Mid-Stage Products11NMIBC Early-Stage Products12NMIBC Pre-clinical and Discovery Stage Products13NMIBC Inactive Products14Non-Muscle Invasive Bladder Cancer Key Companies15Non-Muscle Invasive Bladder Cancer Key Products16NMIBC Unmet Needs17NMIBC Future Perspectives and Conclusion18Analyst Views on NMIBC Future Trends19Appendix20About DelveInsight Related Reports Bladder Cancer Market DelveInsight's "Bladder Cancer Market Insights, Epidemiology, and Market Forecast-2030" report delivers an in-depth understanding of the Bladder cancer, historical and forecasted epidemiology as well as the Bladder cancer market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. 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Jagran New Media has selected Triton Digital to power the distribution and monetization of its podcast content.