Jurgen Klopp’s side have seen their hopes of defending the title vanish in recent weeks amid a dire slump in form, with last weekend’s defeat by rivals Everton representing their first Merseyside derby loss since 1999.
There were at least encouraging signs when Liverpool defeated RB Leipzig 2-0 in the first leg of their Champions League last-16 tie, however, they have now lost their last four top-flight games in succession and face a major fight just to secure a top-four finish.
Sheffield United meanwhile are all but resigned to their fate of relegation, with the Blades 15 points adrift of safety with just 13 games remaining.
Chris Wilder’s side have won just three matches all season, however, they have produced one almighty upset when they defeated Manchester United at Old Trafford. Here’s everything you need to know about the match:
When is it?
The fixture will kick-off at 7:15pm GMT at Bramall Lane.
How can I watch it?
The match is live onSky Sports Premier League and Main Event with coverage starting from 7pm GMT.
Sheffield United: Ramsdale, Baldock, Ampadu, Jagielka, Bryan, Stevens, Norwood, Lundstram, Fleck, McGoldrick, McBurnie
Liverpool: Adrian, Alexander-Arnold, Phillips, Kabak, Robertson, Wijnaldum, Jones, Thiago, Mane, Salah Firmino
Sheffield United: 13/2
Klopp on learning from this season
“We will try everything this season but there are so many things we can learn from it,” he said.“We can really learn a lot of things about what we did right even when the whole world thought it was wrong, and what we did wrong, even when people didn’t realise it.
“And while we are doing that we go through this (tough period) but our football lives - our career - doesn’t end after this season.
“I don’t go and put the finger on my players and blame them for the situation - I don’t do that.
“We are all responsible for it, I am mainly responsible for it. What we go through now, we have to sort problems now, immediately, and in the long term we can get the benefit of what we are going through in the moment.
“It’s not cool but there are much worse things out there than the situation we are in as a football club.”
Liverpool are in poor form with a remarkable number of defensive injuries, and so Sheffield United might feel the champions are there for the taking. Unfortunately, the Reds’ offence remains strong and they will be too much for the Blades. 2-0 Liverpool.