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Run It Back: 5 over/unders for the Raptors' second half
William Lou and Alex Wong predict how the Toronto Raptors will perform in the second half of the NBA season.
William Lou and Alex Wong predict how the Toronto Raptors will perform in the second half of the NBA season.
The new Captain America is finally here.
The COVID-19 pandemic has thrust many Canadians into a precarious financial position. Fortunately, the ...
To match the Black Ops universe more closely, the old Verdansk map has been changed to “Verdansk 84”.
Private sector growth at eight-year high as UK retail sales jump. Services and manufacturing show April boom, prompting hopes of spring spurt in activity
JPMorgan said on Friday it regretted supporting soccer clubs in launching a breakaway European Super League after the plan collapsed earlier this week due to a storm of protest from fans and politicians. JPMorgan provided a 3.5 billion euro ($4.2 billion) grant to the founding clubs to spend on infrastructure and recovery from the impact of the COVID-19 pandemic. The bank was the sole lender to the new soccer competition which was masterminded by Real Madrid's president Florentino Perez.
The "World - Toilet and Kitchen Linen - Market Analysis, Forecast, Size, Trends and Insights. Update: COVID-19 Impact" report has been added to ResearchAndMarkets.com's offering.
When Adam Romano heard he was eligible to get the COVID-19 vaccine in early April, he did what most people in the 21st century would do: he rushed to the Internet to find out all the details. But Romano, who lives in a high-risk downtown Toronto postal code, quickly discovered that details were vague. The province’s website wasn’t very helpful and had limited information on where and when he could get a vaccine. When he finally located the vaccination clinics nearby, another hurdle emerged — finding an open slot for an appointment. “It was kind of, ‘everybody figure it out for yourselves,’” the 35-year-old said. After searching his postal code on Twitter incessantly for weeks, Romano finally stumbled on an account aptly named @to_vaccine. It was a bot, with only 10 followers at the time, that promised to update people periodically on when vaccine appointments became available in his area. A week later, Romano finally secured an appointment at a nearby community clinic, all thanks to the bot account. Behind the bot is Dayi Li, a 28-year-old computer scientist who also lives in the area. His bot quickly amassed a following of a few hundred people within days of its creation and with no advertisement on Li’s part — a testament to how residents in downtown east and west, where rates of COVID-19 are high, continue to exhaust every option available in order to secure a vaccine in the absence of a centralized, provincial booking system. Beyond the city’s downtown, many Ontarians have resorted to relying on social media, namely Twitter, to secure a vaccine, raising equity issues about the province’s confusing rollout of a life-saving shot. Twitter accounts like Vaccine Hunters Canada, for example, have served as a centralized place to receive vaccine information. Li’s bot, while different in design, offers a solution to the same problem for a local audience. The bot works by automatically checking Unity Health’s vaccine booking portal every five minutes — almost mimicking human behaviour without overloading the system for real humans accessing it — to see if new appointments are available in downtown clinics, often due to last-minute cancellations or a dump of new openings. It then tweets out available slots to its growing number of followers. Since the bot went live, Li said a handful of people have managed to secure a vaccine, thanks to its help. “[The bot] saves people time and lets them actually focus on work or whatever they need their time for,” Li said. In Toronto’s M5A, M5B, M4Y and M4X postal codes, vaccines have proved difficult to come by. While anyone over the age of 18 is eligible for one, pop-up clinics have faced some supply challenges, said Unity Health spokesperson Jennifer Stranges. This has led to an inconsistent rollout of available slots, and as a result, people have resorted to constantly refreshing Unity Health’s booking portal in hopes they’ll get lucky. Pure luck is how Li said he secured his own vaccine appointment. While checking the portal at random last Friday morning after dozens of previous attempts, he stumbled upon an available slot by chance. “It got me thinking that this wasn’t a nice experience for anyone,” Li said. At the same time, Li said he noticed people’s frustration grow on Twitter. Some were staying up late hoping the portal would produce available time slots with no luck, leading to more anxiety among people desperate to get vaccinated. By Sunday night, Li had created the Vaccine Bot as a solution. He said he views it as a tool that offers direct transparency for when appointments become available through Unity Health’s portal — something that’s not communicated in the same level of detail by the health network. For Romano, being able to finally secure a vaccine, thanks to Li’s help, has been “unbelievable.” “I don’t think we’ve ever experienced such shared anxiety as a society,” Romano said. “It’s so unfortunate that we had to have this Hunger Games-type of approach in these local areas, when it shouldn’t be this complicated.” Romano added the complicated process makes securing a vaccine difficult for some. “I’m so lucky that I can work from home and that I’m on a computer and that I’m able to do that,” he said. “People who are not tech-savvy are completely left in the dark.” The bot does not provide a 100 per cent guarantee that followers will secure a slot, Li cautioned, as appointments can be filled within seconds, but it provides people with information of when to check. His bot is also limited geographically, as different areas in Toronto have different booking systems depending on which hospital, clinic, pharmacy or health network is behind the vaccine effort. Li advised his followers to use the bot as merely another tool in their arsenal, and to check local health units first for information. As of Thursday, Stranges said Unity Health is still dealing with supply issues, but pop-up clinics in the area like Wellesley Community Centre, led by Sherbourne Health, or Regent Park 40 Oaks, led by Regent Park Community Health Centre, are updating people through their social media channels of when appointments become available. “We recognize there are barriers to accessing the tool,” Stranges added, like lack of computer access. “Our partners will be working with local community agencies and city-funded engagement ambassadors to support clients and address these barriers.” Dr. Homer Tien, a trauma surgeon and head of Phase 2 of Ontario’s COVID-19 Vaccine Distribution Task Force, told the Star that while Ontarians may have to put in extra effort to find relevant vaccine information compared to other jurisdictions, it’s ultimately worth the trouble. “It’s well worth that amount of effort to get your vaccination, both for you personally, but also for us as a society,” Tien said. In the meantime, while Li’s Twitter bot follower count grows, the end goal, he said, is for that number to shrink to zero. “That means everyone gets a vaccine, and the bot becomes completely useless,” Li said. The count has shrunk slightly at times as people secure appointments, he added — a sign of a hopefully bright future ahead. Nadine Yousif is a Toronto-based reporter for the Star covering mental health. Her reporting is funded by the Canadian government through its Local Journalism Initiative. Follow her on Twitter: @nadineyousif_ Nadine Yousif, Local Journalism Initiative Reporter, Toronto Star
Find the best nootropic supplements in 2021 and review top natural brain boosting cognitive enhancement formulas without negative side effects and real benefitsChicago, IL, April 23, 2021 (GLOBE NEWSWIRE) -- Everyone from a Fortune 500 CEO to freshmen in college relies on a new category of supplement known as nootropics to enhance their cognitive ability. Sometimes referred to as “smart drugs”, nootropics are designed to enhance your ability to learn, focus, remember, think critically. Nootropics are even being endorsed by the likes of Joe Rogan, Tim Ferriss, and other celebrities. Although new, there’s plenty of evidence that nootropics can enhance cognition but you need to be careful before buying a nootropic. Thankfully, our research team examined many of the most popular nootropics and determined the best products to boost cognition for 2021 and beyond. Ranking the Best Nootropic Supplements in 2021 Strangely enough, the modern nootropic supplement industry can be traced directly back to the film Limitless. If you haven’t seen the movie, we’ll give you a quick rundown. The protagonist stumbles upon a crazy pill that allows him to become an incredible genius overnight. He runs the stock market, secures a beautiful girlfriend, and lives his dream life. Most of us are average intelligence, so it makes sense why the narrative of the film resonated with so many people around the world. The idea of being able to take a single pill and instantly become an Einstein-level genius is a tough dream to pass up. Is there a real-life Limitless pill? This is a question we get a lot, and it’s also a question that many similar supplement review websites regularly answer. The concept behind the movie involves someone becoming an unprecedented genius after just one pill. Who wouldn’t dream of something so beautifully simple? The unfortunate truth is that most people will never see any version of the Limitless pill. The reason why: the pill does not exist. No supplement will turn you into Albert Einstein, and no pill can help you win the girl of your dreams and dominate the stock market. But the nootropic industry has been around for longer than this blockbuster film. Scientists have worked for centuries on ways to help improve human memory, cognitive function, and general intelligence. Some pills focus primarily on memory, while others are more comprehensive in their potential benefits and applications. Some nootropics improve brain capacity so well that they might actually be able to provide users with improved reflexes and attention spans. These benefits have been observed in multiple research studies, which we will take a closer look at later in the review. Act Now and Take Advantage: See the Number One Brain Boosting Nootropic Supplement in 2021 Because the Limitless movie took nootropics into the mainstream, the past decade has been filled with supplements claiming benefits that they cannot possibly provide for average users. The first result of this mainstream transition has been an oversaturation of the market. Nootropics used to be a niche cottage industry in the larger supplement market, but the infamy of this film helped to take the market to the masses. While this oversaturation has led to the creation of quite a few great formulas from reputable nootropic-producing companies, it has also led to a not-so-great effect: scams. The nootropic industry’s worst scam offenders often prey upon the basic human instinct to want to become smarter. As humans, we evolved to prize intelligence and memory above all else. In fact, it’s how we survived the Ice Age and avoided species extinction. We do not want our readers to get scammed by ineffective nootropic supplements. Avoiding scams is easier than it sounds. We did the groundwork to help consumers get the most efficient and scientifically backed formulas on the current nootropic market. Read on to learn more about our picks for the top nootropic supplements of 2021. We carefully vetted all of the formulas on our list for scientific support, ingredient quality, and company transparency. #1 – Mind Lab Pro Mind Lab Pro is an advanced nootropic stack that combines 11 science backed nootropic compounds to create the ultimate brain supplement. What’s even better is that many of these individual ingredients are able to synergistically work together to amplify the effects of Mind Lab Pro. By taking Mind Lab Pro, you can boost your energy, increase your production of neurotransmitters like GABA, serotonin, and acetylcholine, and protect your brain from oxidative stress. This results in a significant improvement in memory, critical thinking, learning, and focus. Plus, Mind Lab Pro is manufactured in an GMP-certified Lab in the United States and it comes with a standard 30-day money back guarantee so you’ve got plenty of time to evaluate its’ effectiveness. Overall, Mind Lab Pro is one of the few complete nootropic supplements and should be on the top of your list if you’re searching for a nootropic. #2 – Nezena Neuro Focus Neuro Focus is a potent nootropic manufactured by the well-respected company Nezena. It contains several of our favorite nootropic compounds like niacin, glutamic acid, DMAE, L-theanine, and magnesium. All of these ingredients have some form of clinical research backing up their brain boosting claims, which Is why Nezena holds up well compared to other popular nootropics. As the name would imply, Neuro Focus’ main benefit is improved focus. Therefore, you are best suited to choose Neuro Focus if you’re someone who have troubling focusing but many not have problems with critical thinking or memory. Nuzena is also one of the most affordable nootropics available too, so it may be a good option if you’re on a budget or want the most bang for your buck. #3 – Sane Vitaae Sane Vitaae Anti-Aging & Brain Health Formula is unique in that it’s less of a traditional nootropic and more of an anti-aging product. It relies on five main ingredients that it claims can reverse the effects of aging on the brain. These five ingredients are Vitamin D, Folate, a proprietary blend called VitaalMind™, citicoline, and coenzyme Q-10. There is some evidence that Q-10 and citicoline can reduce oxidative stress on the brain, so it appears these claims have some truth to them. Since it is designed more as an anti-aging supplement, Sane Vitaae is probably best suited for older adults suffering from brain fog, mood swings, or memory loss. If you’re younger, say college aged or a little older, you may find another product to be more effective for you. #4 – NaturalCell NeuroActiv6 NaturalCell NeuroActiv6 is a nootropic drink designed specifically to low oxidative stress, reduce cortisol levels, and raise BDNF levels in your brain. It contains natural herbal supplements like ashwagandha, turmeric, grape seed extract, citicoline, and coffee fruit extract to improve cognition. The main mechanism behind Natural Cell is through BNDF production. BNDF stands for “brain-derived neurotrophic factor” and it is a protein critical for the growth of neurons. It also helps to repair damaged cells. Natural Cell increase BNDF production, which increases the rate at which your body can rejuvenate damaged and weaker neurons. Repairing these neurons helps them communicate faster and more efficiently, which is why Natural Cell is an excellent supplement for improving critical thinking, focus, & memory. #5 – ProMind Complex ProMind Complex uses a natural complex of vitamins and minerals like bacopa, St. John’s Wort, huperzine a, ginkgo, and vinpocetine – all of which are staples in the nootropic industry. The only downside is we couldn’t find the exact formula, which is a problem. Despite that, we could discover that ProMind is manufactured in a GMP-certified facility here in the United States and comes with a full 60-day money back guarantee, both of which are good signs. Although we can’t find the exact formula, ProMind contains several of the most well studied and proven brain boosting ingredients. It’s formula is designed to enhance virtually every function of your brain and for that reason, ProMind is a solid choice. #6 – SynapseXT SynapseXT is a unique nootropic designed to strengthen neural connections in the brain and to eliminate tinnitus. Tinnitus is the feeling of ringing in the ears and studies have found tinnitus can cause long term brain damage by weakening certain networks in the brain. The active ingredients in SynapseXT include green tea, hibiscus, vitamin c, hawthorn berry, and vitamin B. All of these ingredients are powerful anti-inflammatory compounds and vitamin B may help strengthen neurotransmitter connections in the brain. SynapseXT is far from your normal nootropic and really designed for people with tinnitus and to repair neural networks. Otherwise, if you don’t have tinnitus, it may not be dosed strong enough to really boost your cognition and may not be a great choice. #7 – Noobru™ Noobru™ is an exciting new nootropic drink that describes itself as “fuel for peak performance.” It comes packed with brain boosting ingredients like, KSM-66 ashwagandha, choline, huperzine A, and Vitamin B6, many of which are backed by dozens of clinical studies. Customers seem to rave about Noobru and its’ ability to boost cognitive performance but many cannot get over the price. A one month’s supply will cost you around $128, which is almost double most of the nootropics we reviewed. Still Noobru is an excellent nootropic drink and it’s easy to mix formula is great if you want something on the road. #8 – Brain Pill It’s not often you see a company pay to have their product clinically studied before coming to market but that’s exactly what Leading Edge Health did with their nootropic product Brain Pill. In their 67-day study, Brain Pill significantly improved learning, memory, concentration, and critical thinking. Their all natural formula contains proven winners like ginkgo biloba, Cognizin, DHA, vinepocetine, bacopa monnieri, and plenty of other cognitive enhancers. Truthfully, the fact Brain Pill is clinically studied should mean we have it higher on our list. When you combine that with a 67-day money back guarantee and a doctor recommendation, it’s no wonder Brain Pill is quickly becoming one of the most popular nootropics. #9 – Nootrogen Nootrogen contains ingredients like bacopa monnieri, glutamine, HCL, green tea, and DMAE extract to enhance cognitive function and to reduce inflammation in the brain. As an added bonus, it also contains glutamic acid, which works as a neurotransmitter in the brain. Studies have shown DMAE supports acetylcholine levels in the brain, an essential neurotransmitter for memory. L-tyrosine also act as a precursor to dopamine, which may help support mood and reduce stress. Overall, Nootrogen is a well formulated product with plenty of proven ingredients. Available for as little as $19.99/bottle, Nootrogen delivers results and provides you with excellent value since it won’t break your piggy bank. #10 – Organixx Ageless Brain Organixx Ageless Brain is brain rejuvenation supplement designed to repair and restore neural connections in the brain to enhance critical thinking, memory recall, and focus. Inside Ageless Brain is a large number of anti-inflammatory ingredients like camu camu, bacopa monnieri, cacao extract, and cinnamon. Organixx claims these ingredients reduce the brain inflammation and oxidative stress that weakens your brain’s ability to make connections between neurons. The science behind neural connections is very complicated and it’s hard to say whether any of these specific ingredients directly affects neurons in the brain. However, bacopa, camu camu, and a few other ingredients are known to enhance cognition and that alone makes Ageless Brain worth trying. #11 – Vitality Now Youthful Brain Vitality Now Youthful Brain is a nootropic specifically targeted towards older adults looking to rejuvenate and restore their cognitive abilities. Endorsed by Dr. Sam Walters, a world-renowned memory expert, Youthful Brain describes as the ultimate supplement to eliminate “senior moments” and to boost memory, concentration, and focus. Youthful Brain’s all-natural formula includes vitamin B12, bacopa, huperzine A, and phosphatidylserine – many of which are backed by dozens of studies. Based on Youthful Brain’s formula, it’s clear that this product is best suited for seniors struggling with memory recall and concentration. Otherwise, you may want to focus on other stronger nootropics. How We Ranked Our nootropic rankings are the result of hundreds of hours of research into dozens of products. Before we compiled our rankings, we only included products that are considered a “nootropic stack”, which requires several ingredients. Products that only list one ingredient are less likely to be effective so they were excluded immediately. Once we had a list of nootropic stacks, we used a number of factors to rank our top nootropic products, including: Product Formula: We looked for products that contained several clinically studied ingredients. We looked for ingredients like DMAE, citicoline, bacopa, ginkgo biloba, and other proven ingredients. We discounted products that mainly used caffeine for its’ cognitive benefits. While caffeine is a strong nootropic (hence why coffee is a staple product), you don’t need to bother with a nootropic if you just want to benefit from caffeine. Finally, ingredient type is just as important as the dosage of each individual ingredient. Therefore, we looked for products with ingredient dosage as close to the dosage used in clinical studies because they are more likely to be effective. Company Reputation: Nootropics have actually been around for decades, but mainstream nootropics are still fairly new. Therefore, we wanted to make sure that we could trust the company behind the product. We researched each company, how they manufacturer their products, what kind of guarantee they gave, and how well their customer support was. Companies with a better reputation and a longer history in the supplement industry were given preference over newer companies as we saw them as more trustworthy. Likewise, a clear money back guarantee and multiple avenues to reach customer service were also preferred. Product Reviews: Our third and final metric for rating nootropic compounds was actual customer reviews. After all, a product can be seemingly dosed properly with the right ingredients but still come up short with users. This is why we considered customer reviews. We looked for thorough reviews from actual customers to gauge their experience with a specific product. Did they feel the product was actually doing anything for them? Were there side effects? Would they recommend it to their friends or family? Did they feel the product was worth the money? These are all questions we did our best to answer so we could truly identify the safest, strongest, and most effective nootropics. Get the #1 Best Ranked Nootropics Supplement for Real Benefits and Results in 2021 Today Benefits of Nootropics Nootropics come in several different varieties. In general, they are designed to boost cognitive functions such as learning, memory, thinking, focus, and creativity. As such, most of the benefits of nootropics relate to these cognitive functions. Testing out the benefits of nootropic ingredients is a fairly easy process too. Unlike products that promote “well-being”, you can clearly test cognitive function. Several studies give a group of subjects a placebo or a potential nootropic compound and then subject them to a number of tests to evaluate performance. There are a variety of different tests performed to evaluate cognitive enhancement too. Learning tests are often the most common but other tests evaluate mental breakdown prevention and fatigue. Others include speech improvement and critical thinking. The main four benefits of nootropics involve the improvement in focus, memory, critical thinking, and learning. However, there are some other benefits related to nootropics as well. Nootropics may improve mood and reduce stress and anxiety. Certain ingredients in nootropic supplements increase levels of neurotransmitters like serotonin, dopamine, and GABA in the brain. These neurotransmitters directly influence your mood, stress levels, and overall feeling on a daily basis. High levels of all three of these neurotransmitters are related to lower stress, better mood, and lower anxiety. Nootropic compounds may provide cognitive protection. Research dating back decades has evaluated herbal extracts for potential cognitive protection benefits. The most definitive study was conducted in 1999 involving huperzine-A. In the study, older monkeys with naturally occurring dementia and younger monkeys with chemical induced cognitive decline were given huperzine A. Researchers were astounded to find that huperzine seemed to reverse the naturally occurring dementia in older monkeys and eliminated cognitive decline in the younger monkeys. Human research is still scarce in this manner, but there’s plenty of anecdotal evidence to back up the animal research involving huperzine-A. Nootropic supplements may reduce inflammation and oxidative stress in the brain. The cause of brain inflammation isn’t entirely known outside of viral infections and other medical conditions. It is believed that the modern diet and lifestyle habits of the average adult likely plays a huge role. Many nootropic supplements contain anti-inflammatory compounds to eliminate inflammation and protect the brain from further damage. Green tea extract and turmeric are the two most widely studied herbal extracts and are two of the most common anti-inflammatory compounds used in supplements nowadays. Cinnamon is another anti-inflammatory compound showing promising results in reducing inflammation caused cognitive decline. Nootropic compounds can support brain health in a variety of ways. Which product you use depends entirely on your individual needs. It’s important you research a product and its’ ingredient profile so you know how effective a supplement could be to meet your individual needs and goals. (HUGE SAVINGS TODAY) Save Big on the #1 Top Ranked Nootropic Smart Pills for Brain Boosting Health Support Who Should Use Nootropics? Nootropics are a unique type of supplement because virtually everyone can benefit from taking them. Entrepreneurs, students, employees, writers, engineers – virtually everybody can benefit from taking a nootropic supplement to enhance their cognitive ability. It is true that different cognitive enhancers affect your brain in a different way and therefore may be best suited for specific individuals. For example, a college student is likely best suited for a nootropic supplement that enhances memory and focus to pass exams. An engineer or an artist may want a nootropic that opens up the brain’s visual functioning and an elderly adult may want a product focused on restoring brain function and memory. Realistically, anybody using their brain in a demanding way can benefit from a nootropic. While they are a fairly new type of supplement, there’s definitive proof cognitive enhancers can support a number of cognitively demanding tasks. (LOWEST PRICE ONLINE) Get the Best Nootropic Cognitive Performance Enhancer Directly from the Official Website for the Biggest Discount Potential Side Effects & Adverse Effects Interest in nootropics dates back over fifty years but unfortunately most nootropic supplements have only been around a few years. Although there’s more research into nootropic compounds, they are still too new for us to have a good understanding of their side effect profile. The one nootropic compounds we do know understand is caffeine. Caffeine is the most widely studied nootropic compound in the world and we know it an effective energy and focus booster. It also can cause side effects like nausea and jitters when too much if you consume too much or you have a sensitivity to it. For the most part, nootropics are well tolerated and do not possess any adverse effects to your health. However, this depends on the product and the individual ingredients used. You have to do your research and get a thorough understanding of the ingredients to make sure they are safe for you. If you are unsure, it is recommended you err on the side of caution and speak to your doctor before taking a nootropic supplement. Recommended Dosage There are dozens of ingredients in nootropic compounds and only a few have established effective doses. Ginkgo biloba is effective at as low as 40mg per day. Bacopa monnieri is effective at around 300-400mg per day. DMAE is normally around a dose of 100mg but doses ranging from 50 to 200mg are common and all found some cognitive improvement in that range. It’s incredibly difficult to identify optimal doses in most nootropic supplements. There is a tremendous amount of interest and research pouring into nootropic compounds, so it will only be a matter of time before we have a better idea of effective doses thankfully. (SPECIAL SAVINGS) Find the Most Popular Cognitive Enhancing Nootropic Brain Booster Supplement Right Now FAQQ. What is a nootropic? A nootropic is a supplemental or pharmaceutical compound that improves any area of cognitive functioning. Cognitive function refers to any mental process involved in thinking, remembering, speaking, decision making, or problem solving, or creativity. In other words, nootropics aid in critical thinking, memory, problem solving, focus, concentration, creativity, and other important brain functions. Q. Are nootropics safe? Since there are so many different vitamins, minerals, and herbal extracts found in nootropics, it is difficult to determine their safety on a broad, generalized manner. So far, nootropics do not appear to possess any common side effects or adverse reactions the way say, weight loss pills do. However, anytime you include a number of ingredients from different sources, there’s a potential risk for side effects to occur. In general, nootropics are seen as safe. There are a number of clinical studies available that have involved popular nootropic compounds like bacopa monnieri, ashwagandha, ginkgo biloba, and others. After a general review of these studies, there are no common side effects or serious health problems linked to these nootropic compounds. Reactions could still happen, but they seem to be very rare. Q. Are there nootropics that mimic Adderall? Adderall is a pharmaceutical compound (technically an amphetamine) that acts as a stimulant and overclocks the brain. It is commonly abused because of its’ ability to provide extreme focus and long-lasting energy. It’s important to understand that Adderall is a pharmaceutical compound meant for specific individuals with certain conditions. Using Adderall outside its’ intended use can be very dangerous and overdoses happen on a regular basis. There is one nootropic compound that can mimic Adderall and that’s caffeine. Caffeine is a fairly potent stimulant found in a variety of drinks, powders, pills, and snacks. It is one of the most widely studied compounds and is known to enhance memory, focus, energy, and concentration. To sum it up, it is unwise to look for compounds that mimic Adderall because of the potency of Adderall and its’ potential side effects. If you want a stimulant that is safer and still has some of the same benefits as Adderall, then caffeine is a fairly safe choice. Q. What’s the best nootropic? It is virtually impossible to say what the best nootropic is because there are so many different individual compounds that each work in a unique manner. For example, there’s plenty of evidence that ashwagandha and ginkgo biloba help enhance memory. On the other side, green tea extract and fish oil are two of the best natural neuroprotective nootropic compounds (to protect the brain). What may be the best nootropic compound for you likely differs from someone else because of your individual goals. Therefore, the best nootropic supplement is the supplement with an ingredient formula designed to meet your individual goals. Q. What do nootropics do? Nootropics are meant to enhance your ability to think, remember, focus, and make decisions. Essentially, any cognitive function you have can be improved through nootropics. They work in a variety of ways. Some ingredients like DMAE and tyrosine help support the function of neurotransmitters (brain chemicals) in the brain to improve brain function. Other herbal extracts like green tea, turmeric, and ashwagandha reduce inflammation and oxidative stress in the brain that may be responsible for poor cognitive abilities. Other nootropic compounds like caffeine are stimulants that improve energy levels and speed up the entire central nervous system. Q. Are nootropics addictive? Most nootropic compounds are not inherently addictive – at least nootropics you can buy over the counter. The only real exception is caffeine, which is one of the most addictive compounds on the planet. Consuming excessive amounts of caffeine can cause caffeine withdrawal and lead to headaches, fatigue, and anxiety. Nicotine is seen as a natural form of nootropic too and is another addictive substance. However, we haven’t found a nootropic supplement with nicotine so it’s mostly irrelevant if you’re looking for nootropics online or at your local store. Aside from caffeine and nicotine, there aren’t any herbal extracts commonly used in nootropics that are known to be addictive. Recap Nootropics are a fairly new type of supplement but there’s already plenty of evidence that they can support cognition in several different ways. Before you pick a nootropic, it’s important to think about what your individual needs are and to pick a nootropic supplement that fits your needs. A college student likely needs a nootropic geared towards memory and learning whereas someone who’s older likely needs a nootropic for cellular rejuvenation and restoration. When done properly, nootropics appear to be a very effective & safe way to increase your overall cognition, improve your brain power, and help you work and think faster and more effectively. Buy the Best Rated, Top Ranked, Most Popular Nootropics Supplement for Powerful Brain Boosting Benefits Today As you walk away from our comprehensive guide to the top nootropic dietary supplements of 2021, we want you to remember a few things. First, consider the various ways that we evaluated nootropic supplements to compile this list. Always look out for the key ingredients in a supplement before making your purchase. For example, nootropic formulas should include natural, quality ingredients. These ingredients should also be provided in sufficient quantities to provide observable results. Most nootropics must be taken consistently over an extended period of time in order to provide you with any serious results. Also remember the viable benefits that the average nootropic can provide you with. The Limitless pill does not exist. Taking a pill will never make you a super-genius, and your reflexes will never become better after a simple supplement. However, many nootropic ingredients have been shown in landmark scientific studies to help improve memory in the short-term. Some pills and their ingredients have also been proven to increase overall brain function and cognitive capacity, all of which are classic indicators of overall intelligence. There are side effects associated with some nootropic supplements, which makes this type of alternative formula a bit different than others on the market. Some nootropics contain high amounts of caffeine, as well as other stimulants. These ingredients can cause addiction and dependency. Additionally, some nootropic formulas can create withdrawal symptoms, violent behavior, and other problems. Some users might experience panic attacks or increased anxiety after taking a new nootropic. We frequently outline how most supplements don’t ultimately contribute to serious side effects, so we should highlight the unique negatives associated with some nootropics. We included more in-depth information about the side effects associated with nootropics in some of the sections above. But as a closing statement, we’d like to recommend that readers carefully evaluate the ingredients present in a nootropic before purchasing it. People who have trouble sleeping, folks who have addictive personalities, and people who are pregnant should consider avoiding nootropics, which can make all of these existing conditions worse. Despite the wealth of potential downsides to nootropics, we still ultimately recommend the use of nootropics for some people who want to improve their brain health and memory. Several of the nootropics ranked on our list have been carefully researched in major scientific studies. The benefits associated with these supplements are nothing compared to the incredible effects experienced by the protagonist in Limitless. But given the disaster that occured for the man in that movie, is that really such a bad thing? Modern nootropics don’t offer the incredible benefit of super-intelligence or lightning fast reflexes, but they can do several important things for people who want to improve their memory and fast-track their cognitive development. As with all dietary supplements, the best route for consumers who want to avoid being scammed is to carefully read the ingredients on any formula they plan to take. After vetting your formula to be sure it is composed of non-addictive and natural ingredients, it might be time to give nootropics a shot! Grand Reveal: Click Here Right Now to Buy the Best Brain Boosting Nootropic Smart Pill for Natural Cognitive Performance Enhancement Official Website: https://promindcomplex.com/ Contact Details: ProMind Complex Email: contact@promindcomplex.com About MarketingByKevin.com This product review is published by Marketing By Kevin. Marketing By Kevin reviews are researched and formulated by a group of experienced natural health advocates with years of dedication and determination to finding the highest quality health products and wellness programs available. It should be noted that any purchase derived from this resource is done at your own peril. It is recommended to consult with a qualified professional healthcare practitioner before making an order today if there are any additional questions or concerns. 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Major players in the interferons market are Roche, Merck, Bristol-Myers Squibb, Biogen Inc, Bayer AG, Zydus Cadila, Novartis AG, Pfizer Inc, Biosidus, and Nanoge. The global interferons market is expected to grow from $7.New York, April 23, 2021 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Interferons Global Market Report 2021: COVID 19 Implications And Growth to 2030" - https://www.reportlinker.com/p06065175/?utm_source=GNW 46 billion in 2020 to $7.61 billion in 2021 at a compound annual growth rate (CAGR) of 2%. The change in growth trend is mainly due to the companies stabilizing their output after catering to the demand that grew exponentially during the COVID-19 pandemic in 2020. The market is expected to reach $8.74 billion in 2025 at a CAGR of 3.5%.The interferons market consists of sales of interferons, the biopharmaceuticals that are produced using living organisms, such as microorganisms and animal cells, and have a high-therapeutic value. The market consists of revenues generated by the establishments by the sales of various types of interferons such as alpha interferons, beta interferons and gamma interferons.The pandemic outbreak of corona virus is expected to drive the growth of interferons market.This is because of the ongoing trials on various drug candidates including interferons as potential therapeutic options for covid-19 treatment.Interferon-beta (IFN-beta) is a naturally occurring protein that controls the body’s antiviral responses.The drug regulators including the Medicines and Healthcare products Regulatory Agency (MHRA) and Health Research Authority (HRA) have approved the initiation of trials evaluating interferons.For example, SNG001 which is an inhalation formulation of interferon-beta-1a that is delivered to the lungs directly via nebulization.The development of interferons involves high R&D costs.The development of interferons is costlier than developing small molecules which are chemically synthesized, involves high operating costs, and requires a greater capital investment.This is because biologic drugs are more complex than small molecules and involve complex manufacturing processes.Additionally, manufacturers have to submit more data to demonstrate the efficacy and safety of these biologics in pre-clinical and clinical studies for successful registration.This makes the registration of biologics a costly and time-consuming process which is restraining the market growth. Due to the high R&D costs, and lengthy testing and manufacturing process, the marketed drugs would be priced much higher than the actual manufacturing costs, and this factor is likely to challenge the market growth.Biologics therapy is expensive and it places a substantial financial burden on the healthcare system.Increasing prevalence of diseases such as hepatitis, MS, and cancers in the world presented an opportunity to evaluate the clinical applications of biosimilars and have stimulated some of the local pharmaceutical companies to produce interferon biosimilar medications to compete (or replace) the original expensive brands.IFNs were initially investigated for their potential as antivirals, however, they are now commonly used in anti-HBV (hepatitis B virus) and anti-HCV (hepatitis C virus) therapy. The therapeutic potential of interferon biosimilars for hepatitis and cancer, coupled with the ongoing studies on interferon biosimilars to have prophylactic or therapeutic effectiveness in SARS (severe acute respiratory syndrome), influenza or another virus pandemic, is contributing to the increasing adoption of interferon biosimilars over expensive biologics.Bayer and Curadev Pvt. Ltd., a drug discovery company based in India, have announced a research collaboration and license agreement for Curadev’s Stimulator of Interferon Genes (STING) antagonist program. The objective of this collaboration between Bayer and Curadev is to discover new drug candidates for the treatment of lung diseases, cardiovascular diseases and other inflammatory diseases. STING antagonists have huge potential for new treatments as STING is known to help in activating the innate immune system in auto-inflammatory diseases.Global interferon drugs market is projected to grow at a rapid pace in the next few years due to the increasing incidence of chronic diseases such as hepatitis-B, hepatitis-C, cancer and multiple sclerosis, the use of interferons in combinational therapies, and advent of novel drug delivery systems.Various types of interferon (IFN) have been used to treat these diseases and an important development in treating some of these diseases was the recognition that the clinical effects of IFN drug could be greatly enhanced by combining it with other drugs.For instance, IFN-? (interferon-alpha) in combination with ribavirin and polyethylene glycol molecule has shown significant improvements in virologic response and without any adverse effects.However, due to the poor stability of interferon-alpha in the gastrointestinal tract, only parenteral administration ensures bioavailability, which is associated with severe side effects.Studies showed that nanoencapsulation of IFN-? within nanoparticles would improve the oral bioavailability of this drug.The use of interferons in combinational therapies, and advent of novel drug delivery systems is therefore expected to drive the market for interferons.Interferons are also being tested for their use in the treatment of COVID-19.Read the full report: https://www.reportlinker.com/p06065175/?utm_source=GNWAbout ReportlinkerReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.__________________________ CONTACT: Clare: clare@reportlinker.com US: (339)-368-6001 Intl: +1 339-368-6001
Germany has decided not to impose limits on the use of Johnson & Johnson's COVID-19 vaccine, the head of the country's vaccine regulator said on Friday, adding the expert panel that decides on its use will meet next week to evaluate new data. Europe's drug regulator backed J&J's vaccine this week after examining cases of a rare blood clotting issue in U.S. adults who received a dose.
Wesley has been sidelined for more than 18 months since rupturing knee ligaments.
MADRID — Most political parties in Spain put aside their differences Friday to condemn a series of death threats mailed to the country's interior minister, the director of the Civil Guard police force and the leader of a far-left political party. But the issue provoked a bitter confrontation between United We Can leader Pablo Iglesias, the recipient of one of the letters, and the far-right candidate in an upcoming regional election in Madrid, who cast doubts on the threats. Vox Party Madrid leader Rocío Monasterio said she was against “all kinds of violence” but, during a radio debate with Iglesias, refused to back away from earlier remarks that she didn't believe her opponent's account. As a result, three left-wing candidates refused to continue talking with the far-right politician and the debate ended abruptly. The threats were delivered in envelopes filled with bullets and accompanied by anonymous letters either demanding the three officials step down from their positions or plainly menacing the recipients and their relatives. Iglesias, who recently stepped down as one of Spain's four deputy prime ministers to run in the May 4 Madrid election, posted a photo on Twitter showing the four bullets he said arrived inside the envelope and the letter addressed to him at the Interior Ministry's headquarters in Madrid. “You have let die our parents and grandparents,” the letter posted by Iglesias read, adding: “Your wife, your parents and you are sentenced to capital punishment. Your time is running out.” Interior Minister Fernando Grande-Marlaska and his appointee, Civil Guard Director General María Gámez, received similar letters. “You have 10 days to step down. The time to laugh at us has ended. National Police. Civil Guard," read the letter addressed to Grande-Marlaska, according to the private news agency Europa Press. The interior minister oversees both police bodies. Monasterio had said that she didn't believe the Spanish government or Iglesias. “They have tricked us since the beginning of the pandemic,” she said during an interview. The far-left candidate said that he refused to whitewash the far-right's hate speech and left a debate hosted by Cadena SER radio later in the day when Monasterio refused to back away from her remarks. Iglesias was followed by two more left-wing candidates, leading the show's host to close the debate. The incumbent conservative Madrid president, Isabel Díaz Ayuso, is set to win next week's election according to the latest polls. But her ability to form a government is likely to hinge on opening the door to Spain's first regional coalition government with the far-right. Aritz Parra, The Associated Press
ANNUAL GENERAL SHAREHOLDERS’ MEETING OF NATUZZI S.P.A.
Judges quash convictions of 39 former postmasters after the UK's most widespread miscarriage of justice.
Everything you need to know about anaphylaxis, a severe and potentially life-threatening reaction to a trigger such as an allergy.
Dublin, April 23, 2021 (GLOBE NEWSWIRE) -- The "5G Chipset Market by Type, Nanometer Size, Technology Integration and Use Cases 2021 - 2028" report has been added to ResearchAndMarkets.com's offering. Due to many factors, chipsets designed for 5G systems have unique factors including the need for optimal energy efficiency. The network effect is clearly evident as the impact of increasingly interconnected IoT systems will cause an acceleration in overall demand for chipsets due to the interdependency of platforms, equipment, and devices. Chipset technology is evolving with many vendors aggressively working towards improving data processing capability as well as energy efficiency and other key factors. In particular, AI chipset-enabled networks of devices and systems will drive substantial change in industrial and workplace environments. It is predicted that nearly 72% of the enterprises will be deploying AI solutions within the enterprise physical facility or application system by 2025. Chipsets will track user location, choice and preference, surrounding environment, machine behavior, and many other data patterns to generate actionable insights and tailored recommendations for each customer. Many important functions, such as connect, collect, and compute, will be powered by the performance of AI chipsets. AI chipsets provide the ability of learning from both users and the environment without the need to utilize explicitly programmed algorithms. AI chipsets are able to detect hidden patterns in new data and perform actions with customized approaches based on specific situations. AI chipsets will allow devices and systems to better understand the surrounding environment and user preferences to optimally execute specific functions. Chipset usage was up substantially during the first quarter of 2021. The industry as a whole is still struggling to rebuild supply in the wake of COVID-19 production shut-downs one year ago. A lack of supply could not have happened at a worse time as 5G is deploying worldwide, especially in the developed nations. However, we see several key companies ramping up production capabilities to meet market needs. This report evaluates the chipset market with an emphasis on the outlook for 5G chipsets. The report analyzes leading chipset vendors, strategies, and offerings. It also provides forecasts for the 5G chipset market by type, chipset size, frequency, technology integration and use cases from 2021 to 2028. Key Topics Covered: 1.0 Executive Summary 2.0 Introduction2.1 Connected Devices2.2 Data Access, Usage, and Chipsets2.3 Chipset Developments2.4 IoT Impact on Wireless and Chipsets2.4.1 Consumer IoT Devices2.4.2 Enterprise IoT Devices2.4.3 Industrial IoT Devices 3.0 Recent Developments in the 5G Chipset Market3.1 Qualcomm3.2 Samsung and Marvell3.3 Gogo3.4 Samsung Galaxy S20 FE 5G3.5 Vivo 4.0 5G Chipset Company Analysis4.1 Analog Devices Inc.4.2 Anokiwave Inc.4.3 Broadcom Inc.4.4 Cavium Inc.4.5 Huawei Technologies Co. Ltd.4.6 Infineon Technologies AG4.7 Intel Corporation4.8 Marvell Technology4.9 MediaTek Inc.4.10 Nokia Corporation4.11 NXP Semiconductors NV4.12 Qorvo Inc.4.13 Qualcomm Incorporated4.14 Renesas Electronics Corporation4.15 Samsung Electronics Co., Ltd.4.16 Texas Instruments Inc.4.17 U-Blox4.18 Unisoc Communications, Inc.4.19 Xilinx Inc. 5.0 Global 5G Chipset Market 2021 - 20285.1 Global 5G Chipset Market by Type 2021 - 20285.1.1 Global 5G Chipset Market by Chipset Use Case 2021 - 20285.1.2 Global 5G Chipset Market by RFIC Type 2021 - 20285.1.2.1 Global 5G Chipset Market by Rf Fe Type 2021 - 20285.2 Global 5G Chipset Market by Application 2021 - 20285.2.1 Global 5G Chipset Market by RAN Infrastructure 2021 - 20285.2.2 Global 5G Chipset Market by Mobile Device Application 2021 - 20285.2.3 Global 5G Chipset Market by Non-Mobile Device Application 2021 - 20285.2.4 Global 5G Chipset Market by Automotive Application 2021 - 20285.3 Global 5G Chipset Market by Frequency 2021 - 20285.4 Global 5G Chipset Market by Nanometer Size 2021 - 20285.5 Global AI Equipped 5G Chipset Market 2021 - 20285.5.1 Total AI Equipped 5G Chipset Market 2021 - 20285.5.2 Global AI Equipped 5G Chipset Market by Technology Type 2021 - 20285.6 Global 5G Chipset Market by Region 2021 - 2028 For more information about this report visit https://www.researchandmarkets.com/r/c8zgja About ResearchAndMarkets.comResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. CONTACT: CONTACT: ResearchAndMarkets.com Laura Wood, Senior Press Manager press@researchandmarkets.com For E.S.T Office Hours Call 1-917-300-0470 For U.S./CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900
Dozens of former subpostmasters who were convicted of theft, fraud and false accounting because of the Post Office’s defective Horizon accounting system have finally had their names cleared by the Court of Appeal. Subpostmasters’ lives were “irreparably ruined” as they lost their jobs, homes and marriages after they were prosecuted by the Post Office – which knew the Fujitsu-developed IT system had “faults and bugs from the earliest days of its operation”, the Court of Appeal heard last month. Lawyers representing 42 former subpostmasters said evidence of serious defects in the Horizon system was “concealed from the courts, prosecutors and defence”, in order to protect the Post Office “at all costs”.
The Bill was cleared 94-1 on Thursday.
TR-1: Standard form for notification of major holdings 1. Issuer Details ISIN GB00B01FLG62 Issuer Name G4S PLC UK or Non-UK Issuer UK 2. Reason for Notification An acquisition or disposal of voting rights 3. Details of person subject to the notification obligation Name HSBC Holdings plc City of registered office (if applicable) London Country of registered office (if applicable) United Kingdom 4. Details of the shareholder Is the shareholder the same as the person subject to the notification obligation, above? No Name City of registered office Country of registered office HSBC Bank plc London United Kingdom 5. Date on which the threshold was crossed or reached 20-Apr-2021 6. Date on which Issuer notified 22-Apr-2021 7. Total positions of person(s) subject to the notification obligation .% of voting rights attached to shares (total of 8.A) % of voting rights through financial instruments (total of 8.B 1 + 8.B 2) Total of both in % (8.A + 8.B) Total number of voting rights held in issuer Resulting situation on the date on which threshold was crossed or reached 0.024000 0.000000 0.024000 375553 Position of previous notification (if applicable) 5.954000 0.001000 5.955000 8. Notified details of the resulting situation on the date on which the threshold was crossed or reached 8A. Voting rights attached to shares Class/Type of shares ISIN code(if possible) Number of direct voting rights (DTR5.1) Number of indirect voting rights (DTR5.2.1) % of direct voting rights (DTR5.1) % of indirect voting rights (DTR5.2.1) GB00B01FLG62 375553 0.024000 Sub Total 8.A 375553 0.024000% 8B1. Financial Instruments according to (DTR5.3.1R.(1) (a)) Type of financial instrument Expiration date Exercise/conversion period Number of voting rights that may be acquired if the instrument is exercised/converted % of voting rights Sub Total 8.B1 8B2. Financial Instruments with similar economic effect according to (DTR5.3.1R.(1) (b)) Type of financial instrument Expiration date Exercise/conversion period Physical or cash settlement Number of voting rights % of voting rights Sub Total 8.B2 9. Information in relation to the person subject to the notification obligation 2. Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entities (please add additional rows as necessary) Ultimate controlling person Name of controlled undertaking % of voting rights if it equals or is higher than the notifiable threshold % of voting rights through financial instruments if it equals or is higher than the notifiable threshold Total of both if it equals or is higher than the notifiable threshold HSBC Holdings Plc HSBC Bank Plc 0.024000 0.024000 10. In case of proxy voting Is there proxy voting? No Name of the proxy holder The number and % of voting rights held The date until which the voting rights will be held 11. Additional Information 12. Date of Completion 22-Apr-2021 13. Place Of Completion London, United Kingdom