Yahoo Movies
Is this Nick Nurse's toughest coaching challenge ever?
Nick Nurse has a globetrotting coaching resume to rival anyone but the Toronto bench boss has a task on his hands to make this season a worthwhile endeavour for the Raptors.
Nick Nurse has a globetrotting coaching resume to rival anyone but the Toronto bench boss has a task on his hands to make this season a worthwhile endeavour for the Raptors.
Clearwater Analytics announced today that it is implementing its SaaS-based data management, accounting, reporting, and analytics solution for Aegon Asset Management (Aegon AM). Clearwater’s solution will help Aegon AM streamline their data, investment accounting and reporting globally.
Luxury Card has announced a partnership with YachtLife, a yacht brokerage with luxury charters at the world’s most popular destinations, from the Mediterranean and New England to Cuba and Mexico. With this partnership, Luxury Card members can now enjoy exclusive discounts on single- and multi-day charters.1
Leading specialised payments platform Paysafe achieves its CarbonNeutral® certification for 2021 and 2022
Signature Bank Reports 2021 First Quarter Results
The Royal Family social media accounts usually wish happy birthday to members of the family.
Dublin, April 21, 2021 (GLOBE NEWSWIRE) -- The "Global Anaplastic Lymphoma Kinase ALK Inhibitors Market, Drug Sales, Price & Clinical Trials Insight 2026" report has been added to ResearchAndMarkets.com's offering. The global anaplastic lymphoma kinase inhibitor market is going to witness high growth during the forecast period which is mainly attributed to the rise in prevalence of anaplastic lymphoma kinase positive cancers and high research and development activities in this sector. The rates at which conventional therapies are failing will further possess unmet need for the development of novel target therapies which will also drive the growth of the market. In addition to this, the robust clinical pipeline and their increasing application in different cancers will drive the market in coming years. Global Anaplastic Lymphoma Kinase ALK Inhibitors Market & Clinical Trials Insight 2026 Report Highlights: Global ALK Inhibitors Market Opportunity: > USD 5 BillionUS Dominates Global ALK Inhibitors Market Sales: >30%Approved ALK Inhibitors: 5 DrugsGlobal & Regional ALK Inhibitors Market Sales Insights (2017-2020)Global & Regional ALK Inhibitors Market Opportunity (2021-2026)Approved ALK Inhibitors Dosage, Patent, Price & Sales InsightsGlobal Clinical Trials Insight By Company, Indication & Phase The progress made by science and technology in last few decades has led to the identification of several potential targets which can be utilized in the drug development process. The characterization of anaplastic lymphoma kinase (ALK) gene and their role in the development and progression of ALK positive cancer has transformed the cancer therapeutics market. The extensive research activities by the researchers have led to the development of novel anaplastic lymphoma kinase inhibitors which belongs to the class of tyrosine receptor kinase and are used in the management of cancer. Till now, multiple anaplastic lymphoma kinase inhibitors have been approved by the regulatory authorities and several others are present in clinical pipeline which are expected to enter the market in next few years. The advent of these drugs in the market has overcome the limitations of conventional therapies such as chemotherapy and radiotherapy. The high target ability and specificity of these inhibitors towards the cancer cells has enhanced the survival rates of cancer patients and also improved the quality of life of patients. Since the approval of first generation anaplastic lymphoma kinase inhibitor in the management of non-small cell lung cancer, researchers have indulge in research activities for the development of next generation inhibitors which can overcome the limitations and can efficiently cross the blood brain barrier for enhanced efficacy. Apart from this, several clinical trials are ongoing to evaluate the efficacy of these drugs in combination with other chemotherapeutic drugs and immune checkpoint inhibitors. The combinational therapy will increase the efficacy of the drug which can better combat the complexity of the cancer. Despite several advantages of anaplastic lymphoma kinase inhibitors in the management of cancer, there are several factors which restrain the growth of the market. The resistance to the drugs during 1-2 year of the therapy is one of the limiting factors which will act as a barrier to the market. Moreover, the high cost associated with the drug will also limit the availability of the drug and increases the financial toxicity on the patient and their families. Currently, US holds the top position in the global market and is expected to maintain its position over the forecast period mainly due to the presence of large pharmaceutical sector which actively invest in research and development activities as well as increasing funding by the government to promote research and development. Apart from this, other regions such Europe, Asia-Pacific and Japan are also expanding their markets to secure their position in the global market. The global anaplastic lymphoma kinase inhibitor market is going to witness high growth rate and is expected to double in next 5 years. Furthermore, the market will be flourished with next-generation ALK inhibitors as well as several combinational therapies in wide range of cancers including neuroblastoma, lymphoma and colorectal cancer. The report includes information about the patent expiration, dosage, price, sales and mechanism of currently approved anaplastic lymphoma kinase inhibitors. In addition to this, several emerging ALK inhibitors along with their clinical trials are also provided in the report. Key Topics Covered: 1. Introduction to Anaplastic Lymphoma Kinase (ALK) Inhibitors1.1 Overview1.2 History of Development 2. ALK Inhibitors as Cancer Therapeutics2.1 Need of ALK Inhibitors in Cancer Therapy2.2 ALK - Potential Target in Cancer Therapy2.3 Mechanism of Action 3. ALK Inhibitors in Lung Cancer3.1 Role of ALK Inhibitors in Lung Cancer3.2 On Going Research & Development 4. ALK Inhibitors in Neuroblastoma4.1 Role of ALK Inhibitor in Neuroblastoma4.2 On Going Clinical Research 5. ALK Inhibitors in Lymphoma5.1 Role of ALK in Lymphoma5.2 On Going Clinical Research 6. ALK Inhibitors in Other Cancers6.1 ALK Inhibitor in Colorectal Cancer6.2 ALK in Renal Cell Carcinoma6.3 ALK Inhibitor in Inflammatory Myofibroblastic Tumor 7. Crizotinib (Xalkori) - Clinical & Commercial Insight7.1 Overview7.2 Patents & Assignees7.3 Dosage & Price Analysis7.4 Sales Analysis 8. Certinib (Zykadia) - Clinical & Commercial Insight8.1 Overview8.2 Patents & Assignees8.3 Dosage & Price Analysis 9. Alectinib (Alecensa) - Clinical & Commercial Insight9.1 Overview9.2 Patents & Assignee9.3 Dosage & Price Analysis9.4 Sales Analysis 10. Brigatinib (Alunbrig) - Clinical & Commercial Insight10.1 Overview10.2 Patent Information10.3 Dosage & Price Analysis10.4 Sales Analysis 11. Lorlatinib (Lorbrena) - Clinical & Commercial Insight11.1 Overview11.2 Dosage, Patent & Price Analysis11.3 Sales Analysis 12. Emerging Novel ALK Inhibitors in Cancer12.1 Ensartinib12.2 Entrectinib (RXDX-101)12.3 TPX-013112.4 TQ-B313912.5 Belizatinib (TSR-011)12.6 CEP-3744012.7 Alkotinib 13. ALK Inhibitor Market Analysis - Clinical Trial Insight13.1 By Phase13.2 By Company13.3 By Country13.4 By Patient Segment 14. ALK Inhibitors Drug Market14.1 Current Market Scenario14.2 Global & Regional Market Analysis 15. ALK Inhibitor Drug Market by Product15.1 First Generation ALK Inhibitor15.2 Second Generation ALK Inhibitor15.3 Third Generation ALK Inhibitor 16. Anaplastic Lymphoma Kinase (ALK) Inhibitors Clinical Trials Insight16.1 Research16.2 Preclinical16.3 Phase-I16.4 Phase-I/II16.5 Phase-II16.6 Phase-III 17. Marketed Anaplastic Lymphoma Kinase (ALK) Inhibitors Clinical Insight17.1 ALUNBRIG17.2 Lorbrena/Lorviqua17.3 Alecensa17.4 Jikadia/ Zykadia17.5 Xalkori 18. ALK Inhibitor - On Going Research & Development18.1 Lorbrena Overcomes Xalkori as Front-Line Therapy in NSCLC18.2 Comparable Time to Treatment Deterioration of Lorlatinib & Crizotinib inPatients with NSCLC18.3 FDA Approved CDx Assay for Lorlatinib in ALK Positive NSCLC18.4 TPX-0131 Overcomes ALK Mutations in Preclinical Models 19. ALK Inhibitor Drug Market Future Prospects19.1 ALK Inhibitor Future Forecast19.2 Future Market Opportunity of ALK Inhibitor 20. ALK Inhibitor Drug Market Dynamics20.1 ALK Inhibitor Drug Market Favorable Parameters20.2 Barriers to ALK Inhibitor Drug Market 21. Competitive Landscape21.1 Astellas Pharma21.2 AstraZeneca21.3 Betta Pharmaceuticals21.4 GlaxoSmithKline21.5 Merck21.6 Novartis21.7 Pfizer21.8 Roche21.9 Takeda Pharmaceuticals21.10 Turning Point Therapeutics For more information about this report visit https://www.researchandmarkets.com/r/bzeslm CONTACT: CONTACT: ResearchAndMarkets.com Laura Wood, Senior Press Manager press@researchandmarkets.com For E.S.T Office Hours Call 1-917-300-0470 For U.S./CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900
The "Qatar Projects H1 2021 - Outlook of Major Projects in Qatar - MEED Insights" report has been added to ResearchAndMarkets.com's offering.
It's the seventh engagement for the mother-of-five who has been married three times.
Japanese Prime Minister Yoshihide Suga has cancelled plans to visit India and the Philippines during his country's extended holiday starting in late April amid a sharp rise in COVID-19 cases, a senior government spokesman said on Wednesday. Japan's government is considering a state of emergency for Tokyo and several other prefectures, while Indian data showed on Wednesday there had been 295,041 new infections nationwide overnight and 2,023 deaths, India's highest in the pandemic. Asked about media reports that Suga's trip to the two countries has been cancelled, Chief Cabinet Secretary Katsunobu Kato said: "In order to take all possible coronavirus countermeasures, it has been decided Prime Minister Suga won't take any overseas trips during the Golden Week."
The "Green Cement Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2021-2026" report has been added to ResearchAndMarkets.com's offering.
3D Printing Market Research Report - Global Forecast to 2025 - Cumulative Impact of COVID-19 Market Statistics: The report provides market sizing and forecast across five major currencies - USD, EUR GBP, JPY, and AUD.New York, April 21, 2021 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "3D Printing Market Research Report - Global Forecast to 2025 - Cumulative Impact of COVID-19" - https://www.reportlinker.com/p06062991/?utm_source=GNW This helps organization leaders make better decisions when currency exchange data is readily available.1. The Global 3D Printing Market is expected to grow from USD 14,932.56 Million in 2020 to USD 32,982.67 Million by the end of 2025.2. The Global 3D Printing Market is expected to grow from EUR 13,093.15 Million in 2020 to EUR 28,919.83 Million by the end of 2025.3. The Global 3D Printing Market is expected to grow from GBP 11,639.84 Million in 2020 to GBP 25,709.80 Million by the end of 2025.4. The Global 3D Printing Market is expected to grow from JPY 1,593,683.37 Million in 2020 to JPY 3,520,087.61 Million by the end of 2025.5. The Global 3D Printing Market is expected to grow from AUD 21,684.07 Million in 2020 to AUD 47,895.23 Million by the end of 2025.Market Segmentation & Coverage:This research report categorizes the 3D Printing to forecast the revenues and analyze the trends in each of the following sub-markets:Based on Geography, the 3D Printing Market studied across Americas, Asia-Pacific, and Europe, Middle East & Africa. The Americas region surveyed across Argentina, Brazil, Canada, Mexico, and United States. The Asia-Pacific region surveyed across Australia, China, India, Indonesia, Japan, Malaysia, Philippines, South Korea, and Thailand. The Europe, Middle East & Africa region surveyed across France, Germany, Italy, Netherlands, Qatar, Russia, Saudi Arabia, South Africa, Spain, United Arab Emirates, and United Kingdom. Company Usability Profiles:The report deeply explores the recent significant developments by the leading vendors and innovation profiles in the Global 3D Printing Market including 3D Systems, Inc., ARC Group Worldwide, Inc., Beijing Tiertime Technology Co., Ltd., Carbon, Inc., EnvisionTEC, EOS GmbH, ExOne Company, General Electric Company, Groupe Gorge Company, Hewlett-Packard Development Company, L.P., Höganäs AB, Koninklijke DSM N.V., Materialise NV, Mcor Technologies Ltd, Nano Dimension, Optomec Inc., Proto Labs, Ltd., Renishaw PLC, SLM Solutions Group AG, Stratasys, Ltd., taulman3D, LLC, Ultimaker BV, and voxeljet AG. Cumulative Impact of COVID-19:COVID-19 is an incomparable global public health emergency that has affected almost every industry, so for and, the long-term effects projected to impact the industry growth during the forecast period. Our ongoing research amplifies our research framework to ensure the inclusion of underlaying COVID-19 issues and potential paths forward. The report is delivering insights on COVID-19 considering the changes in consumer behavior and demand, purchasing patterns, re-routing of the supply chain, dynamics of current market forces, and the significant interventions of governments. The updated study provides insights, analysis, estimations, and forecast, considering the COVID-19 impact on the market.FPNV Positioning Matrix:The FPNV Positioning Matrix evaluates and categorizes the vendors in the 3D Printing Market on the basis of Business Strategy (Business Growth, Industry Coverage, Financial Viability, and Channel Support) and Product Satisfaction (Value for Money, Ease of Use, Product Features, and Customer Support) that aids businesses in better decision making and understanding the competitive landscape.Competitive Strategic Window:The Competitive Strategic Window analyses the competitive landscape in terms of markets, applications, and geographies. The Competitive Strategic Window helps the vendor define an alignment or fit between their capabilities and opportunities for future growth prospects. During a forecast period, it defines the optimal or favorable fit for the vendors to adopt successive merger and acquisition strategies, geography expansion, research & development, and new product introduction strategies to execute further business expansion and growth.The report provides insights on the following pointers:1. Market Penetration: Provides comprehensive information on the market offered by the key players2. Market Development: Provides in-depth information about lucrative emerging markets and analyzes the markets3. Market Diversification: Provides detailed information about new product launches, untapped geographies, recent developments, and investments4. Competitive Assessment & Intelligence: Provides an exhaustive assessment of market shares, strategies, products, and manufacturing capabilities of the leading players5. Product Development & Innovation: Provides intelligent insights on future technologies, R&D activities, and new product developmentsThe report answers questions such as:1. What is the market size and forecast of the Global 3D Printing Market?2. What are the inhibiting factors and impact of COVID-19 shaping the Global 3D Printing Market during the forecast period?3. Which are the products/segments/applications/areas to invest in over the forecast period in the Global 3D Printing Market?4. What is the competitive strategic window for opportunities in the Global 3D Printing Market?5. What are the technology trends and regulatory frameworks in the Global 3D Printing Market?6. What are the modes and strategic moves considered suitable for entering the Global 3D Printing Market?Read the full report: https://www.reportlinker.com/p06062991/?utm_source=GNWAbout ReportlinkerReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.__________________________ CONTACT: Clare: clare@reportlinker.com US: (339)-368-6001 Intl: +1 339-368-6001
"This verdict does not bring back Mr Floyd," wrote Bridgerton producer Shonda Rhimes. "But justice is truth."
BUDAPEST, Hungary — Hungary's right-wing government and the liberal leadership of the country's capital city are absorbed in a conflict over a hospital for the homeless that may soon be forced to close its doors. The hospital provides medical care, social services and shelter to more than 1,000 people annually. Equipped with nearly 75 beds, state of the art facilities, a temporary hostel and outpatient treatment, it is the only such hospital in Budapest, which suffers from a high rate of homelessness. Yet the Hungarian government has ordered the Budapest Methodological Center of Social Policy, which runs the city-funded hospital, to vacate the state-owned building the facility occupies, creating uncertainty for the hundreds of people receiving treatment there and a clash with the capital's liberal mayor. “If there is no alternative site, we are not moving out. They can send the police after us, they can pull us out by force, but we’re not leaving on our own,” Budapest Mayor Gergely Karacsony told The Associated Press. Karacsony, an outspoken opponent of Hungary's central government under Prime Minister Viktor Orban, says he spent months asking government officials to allow the hospital either to remain in place or to relocate to another suitable building. The office of Andrea Mager, Hungary's minister without portfolio for the development of public assets, told the AP that an unspecified health care institute will be moved into the property, and that Budapest's government “has known for nearly a year that the building...will be renovated, (but) has not taken any substantive steps to relocate” the hospital. After extending the deadline, the government now says the hospital has until June 30 to relocate. Dr. Franciska Csortos, the head of inpatient care at the hospital, says that Hungary’s public health authority requires homeless patients needing chronic care to be treated at approved facilities that can provided specialized medical attention. But the only other such facility in Budapest is full, she said, meaning her 75 patients and over 150 people staying at the facility's temporary hostel would have nowhere else to go if the hospital has to vacate the building. “(The patients) are in such a condition that they absolutely require hospital care. We cannot release them into temporary shelters,” Csortos said. With Hungary's healthcare system already overburdened by the nearly 9,000 people hospitalized with COVID-19, allowing homeless patients to be returned to the street could have fatal consequences, Karacsony said. "We will simply not leave these people on their own. We would not be sending them to the street, but to their deaths,” the mayor said. Hungary’s government has long taken a hard-line approach to homelessness. After courts struck down two laws that banned sleeping rough, the ruling Fidesz party used its two-thirds majority in parliament to pass a constitutional amendment in 2018 that criminalized “habitual residence in a public space.” Police can issue citations to unhoused people and require them to perform community service. Someone found sleeping in a public place three times can be imprisoned. Dora Papadopulosz, a spokesperson for the From Streets to Homes Association, a Budapest-based housing rights organization, said the decision to evict the hospital is part of a trend of anti-homeless policies enacted by Orban's government that in her view reflect a social agenda that favours the middle and upper classes while ignoring the needs of the poor. “If people in the government think it’s fair to bring homeless people to jail, then we shouldn’t be surprised that they simply don’t care about the most vulnerable people in society,” Papadopulosz said. In a 2020 report, housing non-profit Habitat For Humanity estimated that some 3 million people in Hungary suffer from housing poverty, defined as people with debts who have difficulty affording monthly rent, people who live in overcrowded or very poor quality apartments, or those who struggle to pay household bills. Some estimates place the number of homeless in the country at 30,000. Adding to the strain, rent prices in Hungary increased by 60% between 2007 and 2019, but salaries have not kept pace, according to Eurostat, the official statistical office of the European Union. Andrea Toth, who is being treated at the evicted hospital, said she and other patients are uncertain of where they will go if the facility must relocate, but she trusts the mayor will make sure they are sheltered. “We don’t know what the end result will be. All we know is that no one will go out on the street. Gergely Karacsony said that himself," Toth said. "The government didn’t promise anything. Their motto should be, ‘Live and let live.’” Justin Spike, The Associated Press
The entrepreneur is said to have lobbied the Prime Minister after being unable to get assurance from the Treasury on overseas staff working in the UK.
The selection process will consist of preliminary screening and shortlisting which will be based on the eligibility criteria, qualifications, experience
The two teams were part of a club of 12 European clubs that banded together to form a breakaway midweek competition, governed by the founding members, to rival the UEFA Champions League.
Sterling held its ground against the dollar on Wednesday as traders assumed a rise in inflation in March would have little impact on monetary policy and waited for crucial activity and retail sales data due at the end of the week. Consumer price inflation rose to 0.7% in March after dipping to just 0.4% in February, as global oil prices rose and retailers scaled back their COVID-driven discounts. "CPI isn't a story that will be driving sterling in the short term", said Jeremy Stretch, a foreign exchange strategist at CIBC Financial markets.
‘I think her father should move over,’ singer says
The "2021 Microbiome Market Trend" report has been added to ResearchAndMarkets.com's offering.
Dublin, April 21, 2021 (GLOBE NEWSWIRE) -- The "Global Gunshot Detection System Market Outlook 2025" report has been added to ResearchAndMarkets.com's offering. A gunshot detection system detects and conveys the location of gunfire or any other weapon. Also known as gunshot locators or shooter detection systems, these systems work by accurately and reliably detecting live ammunition (gunshots), with the help of acoustic, optical, or any other type of sensors, as well as a combination of these sensors. Gunshot detection systems are widely used by military, law enforcement, and security agencies. The global gunshot detection systems market is anticipated to grow with a robust CAGR of nearly 20% during the forecast period, i.e., 2018-2025. Factors such as the rising demand for gunshot detection systems in smart cities globally, coupled with the numerous benefits associated with gunshot detection systems are anticipated to promote the growth of the global gunshot detection systems market during the forecast period. Additionally, factors such as the growing need for advanced security systems in smart cities on account of rising incidences of weapon related fierceness, is anticipated to drive the market growth.The global gunshot detection systems market consists of numerous segments, which include segmentation by product type, installation, application, and by region. The market is further segmented by product type into indoor and outdoor, out of which, the outdoor segment held the largest market share in 2017, owing to the wide utilization of these systems by the law enforcement agencies as well as in the defense sector so as to minimize mass killing and to determine the direction of incoming enemy gunfire during a warfare.Based on region, the global gunshot detection systems market is segmented by regions into North America, Latin America, Europe, Asia Pacific, and the Middle East & Africa, out of which, the market in North America is forecasted to grab the highest market share of close to 60% in 2021. Increasing concern for the firearm-related deaths in the region and the stringent regulatory policies and schemes that raises the requirement for the installation of such systems are some of the factors anticipated to drive the growth of the market in the region.Some of the prominent players in the global gunshot detection systems market are ShotSpotter, Inc., Shooter Detection Systems (SDS), Raytheon Technologies Corporation, AmberBox, Inc., Louroe Electronics, Safety Dynamics, Inc., Microflown AVISA, Rheinmetall AG, QinetiQ Group, and Databuoy Corporation.Key Topics Covered: Global Gunshot Detection System Market1. Global Gunshot Detection System Market Overview2. Global Gunshot Detection System Market Segmentation2.1. By Product Type2.2. By Installation2.3. By Application2.4. By Geography/Region3. Global Gunshot Detection System Market Dynamics3.1. Growth Drivers3.2. Challenges3.3. Opportunities3.4. Trends3.5. Impact Analysis4. North America Gunshot Detection System Market (2018-2025)4.1. Market Overview4.2. Segmentation by Product Type4.3. Segmentation by Installation4.4. Segmentation by Application4.5. Segmentation by Country5. Asia Pacific Gunshot Detection System Market (2018-2025)5.1. Market Overview5.2. Segmentation by Product Type5.3. Market Segmentation by Installation5.4. Segmentation by Application5.5. Segmentation by Country6. Europe Gunshot Detection System Market (2018-2025)6.1. Market Overview6.2. Segmentation by Product Type6.3. Segmentation by Installation6.4. Segmentation by Application6.5. Segmentation by Country7. Latin America Gunshot Detection System Market (2018-2025)7.1. Market Overview7.2. Segmentation by Product Type7.3. Segmentation by Installation7.4. Segmentation by Application7.5. Segmentation by Country8. Middle East & Africa Gunshot Detection System Market (2018-2025)8.1. Market Overview8.2. Segmentation by Product Type8.3. Segmentation by Installation8.4. Segmentation by Application8.5. Segmentation by Country9. Competitive Landscape9.1. ShotSpotter, Inc.9.2. Shooter Detection Systems (SDS)9.3. Raytheon Technologies Corporation9.4. AmberBox, Inc.9.5. Louroe Electronics9.6. Safety Dynamics, Inc.9.7. Microflown AVISA9.8. Rheinmetall AG9.9. QinetiQ Group9.10. Databuoy CorporationFor more information about this report visit https://www.researchandmarkets.com/r/3jpbte CONTACT: CONTACT: ResearchAndMarkets.com Laura Wood, Senior Press Manager press@researchandmarkets.com For E.S.T Office Hours Call 1-917-300-0470 For U.S./CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900