Matt Kane plots ambitious return to Triangle biotech scene with Tune Therapeutics

·2 min read

N&O Innovation and Technology Newsletter: December 3, 2021

Enjoying the newsletter? Subscribe to it here, and share with your friends and colleagues.

Matt Kane is back.

After successfully taking his last company, Precision Biosciences, to an IPO, Kane stepped down from Precision earlier this year.

Now, he’s tackling a new frontier of gene therapy -- epigenetics -- and is getting some serious backers, including locally based Hatteras Venture Partners and the Emerson Collective, the organization founded by Steve Jobs’ widow Laurene Powell Jobs.

I spoke with Kane about the new company, Tune Therapeutics, and what he is trying to do with it.

[Read more here]

Philanthropy funds the Innovate Raleigh fellowship. Consider supporting philanthropy-funded journalism by going to

Matthew Kane, CEO of Tune Therapeutics
Matthew Kane, CEO of Tune Therapeutics

(Matt Kane)

Tech news from the Triangle

  • A vacant Kroger in Raleigh will soon be transformed into lab space, as Triangle’s life sciences market continues to grow. [N&O]

  • Pryon, Raleigh AI startup founded by entrepreneur who helped build parts of Amazon’s Alexa, preps for pivotal year. [N&O]

  • Former PowerSecure CEO’s new startup pulls in $8M. [Inno]

  • Google delays January office return because of omicron variant. [Protocol]

What I’m reading

  • These 5 NC counties are considered more economically ‘distressed’ than they were a year ago. [N&O]

  • Jack Dorsey’s big week: leaving Twitter and diving further into crypto. [Economist]

  • Big Tech Privacy Moves Spur Companies to Amass Customer Data. [WSJ]

  • Bezos: Future Humans ‘Will Visit the Earth the Way You Visit Yellowstone’ [Gizmodo]

  • Didi Chuxing, the Chinese ride-hailing company, begins delisting its New York-traded shares just months after offering. [NYT]

  • Dick Vitale made a promise to Jimmy V he won’t break, even as cancer tries to stop him. [N&O]

  • Ghost Kitchens are proving to be a messy business. [WSJ]

  • The effective fomo of Spotify Wrapped. [The Verge]

Other Triangle business

  • It’s been nearly a week since 3 people were shot at a Durham mall. Here’s what we know. [N&O]

  • Chapel Hill gives developer ‘huge responsibility’ to shape downtown skyline, future. [N&O]

  • UNC board members were kept in dark about legislature’s order to move offices to Raleigh. [N&O]

Let me know what you’re seeing. Email me at Tweet me @zeanes. Call me at 919-829-4516.

Zachery Eanes is the Innovate Raleigh reporter for The News & Observer and The Herald-Sun. He covers technology, startups and main street businesses, biotechnology, and education issues related to those areas.

This newsletter was produced with financial support from a coalition of partners led by Innovate Raleigh as part of an independent journalism fellowship program. The N&O maintains full editorial control of the work. Learn more; go to

Our goal is to create a safe and engaging place for users to connect over interests and passions. In order to improve our community experience, we are temporarily suspending article commenting