A double from Scott McTominay secured a significant victory for Erik ten Hag and his side, with the Old Trafford club now back in the top six.
Ten Hag made a number of significant selection decisions before the 2-1 win, with Marcus Rashford and Anthony Martial left out of the starting side.
Bournemouth, meanwhile, were also midweek winners as a 2-0 win at Crystal Palace extended their unbeaten run in the league to four games.
Here’s everything you need to know. Get the latest Manchester United vs Bournemouth odds and tips here.
When is Manchester United vs Bournemouth?
Manchester United vs Bournemouth is due to kick off at 3pm GMT on Saturday 9 December at Old Trafford.
How can I watch it?
The game will not be broadcast live in the United Kingdom. Extended highlights will be shown on Match of the Day, which airs on BBC One at 10.20pm GMT. The programme will also be available via the BBC iPlayer.
Manchester United XI: Onana; Dalot, Maguire, Shaw, Reguilon; McTominay, Amrabat, Fernandes; Antony, Martial, Garnacho.
Bournemouth XI: Neto; Smith, Zabarnyi, Senesi, Kerkez; Cook, Christie; Semenyo, Kluivert, Tavernier; Solanke.
Manchester United win 5/9
Bournemouth win 19/4
Another win for Manchester United. Manchester United 3-1 Bournemouth.