Brazilian goalkeeper Alisson has missed the last three games with a muscle injury suffered in the high-profile 1-1 draw with title rivals Manchester City last month but rejoined the squad on Thursday and is fit to start this afternoon.
"Alisson looks good," Reds boss Jurgen Klopp said on Friday. "I don't know if good enough for tomorrow, I'll have to check that with the medical department and with Ali."
Joel Matip is absent for Liverpool after suffering a serious knee injury against Fulham which is likely to rule him out for the rest of the season, with young Quansah preferred to Ibrahima Konate alongside captain Virgil van Dijk in the heart of defence.
"Mac Allister doesn't look good, so we'll have to see day by day," Klopp noted.
"They were pretty hopeful after the game that it was not that serious but in this time of year if you're out for five days it's 12 games pretty much. So we have to wait there and see how he shows up today.
"I don't expect him to be ready for tomorrow but I don't know about after that. It's touch and go."
Wataru Endo keeps his place at the base of Liverpool's midfield as Mac Allister misses out, with Ryan Gravenberch beating Curtis Jones and Harvey Elliott for the Argentine's place.
Darwin Nunez returns to lead the attack while Kostas Tsimikas gets the nod at left-back to continue his rotation with Joe Gomez.
Liverpool XI: Alisson, Alexander-Arnold, Quansah, Van Dijk, Tsimikas, Endo, Szoboszlai, Gravenberch, Salah, Nunez, Diaz
Subs: Gomez, Konate, Jones, Gakpo, Elliott, Doak, McConnell, Kelleher, Bradley
Injured: Matip, Mac Allister, Jota, Robertson, Bajcetic, Thiago
Time and date: 12:30pm GMT on Saturday December 9, 2023
Venue: Selhurst Park
TV channel: TNT Sports