Diogo Jota opened the scoring for the hosts after nine minutes, embarking on a solo run that saw him navigate past four defenders before planting the ball into the bottom corner.
Toulouse responded seven minutes later as Thijs Dallinga perfectly timed his run from the halfway line into the box, effortlessly slotting home in the Group E clash.
The rest of the match belonged to Liverpool as Wataru Endo headed them back in front just past the half-hour mark. Four minutes later Darwin Nunez extended their lead with a shot from a tight angle, capitalising on a rebound inside the box.
Nunez nearly netted again in the 65th minute but his shot from the right side of the box struck the post after a superb run. Nevertheless, Ryan Gravenberch capitalised on the rebound to score Liverpool's fourth goal.
Three minutes into stoppage time late substitute Mohamed Salah completed the thrashing with a well-placed shot into the top corner from closer range having bemused his marker.
Liverpool top the group by five points over Union Saint Gilloise, who beat visitors LASK 2-1, and Toulouse, with both teams on four points. LASK are bottom without a point.
Liverpool vs Toulouse latest news
22:52 , Jonathan Gorrie
Thanks for joining Standard Sport's LIVE coverage of Liverpool's win over Toulouse.
Find our report and reaction below!
Klopp hails 'incredible' Gravenberch after Liverpool beat Toulouse
22:51 , Jonathan Gorrie
Jurgen Klopp hailed Liverpool midfielder Ryan Gravenberch after his side romped to a 5-1 win over Toulouse in the Europa League on Thursday night.
The Reds are now all but there in terms of qualification for the knockout rounds after maintaining their 100% record in a competition Klopp has already vowed to take seriously.
Reds remain unbeaten in Europa League with big win at Anfield
22:17 , Jonathan Gorrie
Liverpool ran out 5-1 winners over Toulouse to maintain their 100% record in the Europa League.
Diogo Jota continued his love affair with Europe's second competition, scoring his eighth goal in seven appearances, and although Thijs Dallinga levelled for the visitors, Wataru Endo got off the mark in Liverpool colours and Darwin Nunez added another to put Jurgen Klopp's men in charge before half-time.
Nunez then hit the post of an open goal just after the hour, but Ryan Gravenberch tucked in the rebound and substitute Mohamed Salah added a fifth in stoppage time to leave Liverpool - three points off the top of the Premier League - looking strong on all fronts as they face an intense run of fixtures.
Liverpool vs Toulouse: GOAL! Mohamed Salah '90
21:53 , Jonathan Gorrie
90 mins: Salah adds a late fifth!
Liverpool vs Toulouse: Not a result to be taken lightly
21:42 , Jonathan Gorrie
81 mins: Liverpool might have been strong favourites but to put four goals up against the second best team in the group is hardly easy.
Liverpool vs Toulouse: GOAL! Ryan Gravenberch '65
21:26 , Jonathan Gorrie
65 mins: GOAL!
Nunez hits the post from close range after brilliant work to round a defender and the goalkeeper but Ryan Gravenberch is there to score the rebound!
Liverpool vs Toulouse: Game still on
21:16 , Jonathan Gorrie
56 mins: Hard to suggest Liverpool aren't in control of the game but Toulouse still proving they can cause problems.
Liverpool vs Toulouse: CHANCE FOR TOULOUSE!
21:07 , Jonathan Gorrie
47 mins: Alexander-Arnold clears one off the line after Kelleher's mistake!
Liverpool vs Toulouse: Back underway!
21:05 , Jonathan Gorrie
Away we go for the second-half!
Liverpool vs Toulouse: Half-time
20:50 , Jonathan Gorrie
Jota, Endo and Nunez with the goals as Liverpool head into the break with a healthy lead.
Liverpool vs Toulouse: Into added time
20:47 , Jonathan Gorrie
45 mins: 2 minutes added on.
Liverpool vs Toulouse: Firepower too much
20:45 , Jonathan Gorrie
43 mins: At points, Toulouse have looked dangerous.
The sheer number of quality forwards Klopp has in his squad, however, make it hard for anyone to deal with keeping this team out.
Liverpool vs Toulouse: GOAL! Darwin Nunez '34
20:37 , Jonathan Gorrie
34 mins: GOAL!
More great work from Gravenberch, driving deep and freeing Jones. He sees his shot blocked and it falls to Nunez, who fires one into the roof of the net.
Liverpool vs Toulouse: GOAL! Endo '30
20:33 , Jonathan Gorrie
30 mins: GOAL!
Endo meets Alexander-Arnold's floated ball into the box with a powerful header.
Liverpool vs Toulouse: CHANCE FOR LIVERPOOL!
20:30 , Jonathan Gorrie
28 mins: Ryan Gravenberch does well to work some space for a shot but Restes does well to get down to it.
Liverpool vs Toulouse: Reds losing a bit of composure
20:27 , Jonathan Gorrie
24 mins: While it would be too much to say Liverpool are on the ropes, they are perhaps trying to rush things too much.
Toulouse very tough to break down and a danger on the counter, as we've already seen.
Liverpool vs Toulouse: GOAL! Thijs Dallinga '15
20:18 , Jonathan Gorrie
15 mins: GOAL!
Thijs Dallinga rounds off a lovely counter with a composed finish.
Liverpool vs Toulouse: CHANCE FOR LIVERPOOL!
20:16 , Jonathan Gorrie
13 mins: Restes does well to stop Nunez's shot after the striker shows quick feet to create space following Jota's flick.
Liverpool vs Toulouse: GOAL! Diogo Jota '8
20:11 , Jonathan Gorrie
08 mins: Well, that slow-ish Liverpool start didn't last long.
Jota with a brilliant goal, running from deep, feinting past a defender and firing in a fine finish.
Liverpool vs Toulouse: Visitors not afraid
20:10 , Jonathan Gorrie
06 mins: Toulouse, playing with a two-man frontline, are hardly looking huge underdogs here.
They're more than willing to engage Liverpool high up the pitch.
Should make for an entertaining game.
Liverpool vs Toulouse: Cagey start
20:08 , Jonathan Gorrie
05 mins: Not a huge amount of joy for Liverpool in the opening stages.
Liverpool vs Toulouse: KICK-OFF!
20:02 , Jonathan Gorrie
Away we go at Anfield!
Liverpool vs Toulouse: Head to head (h2h) history and results
19:38 , Jonathan Gorrie
Liverpool wins: 2
Toulouse wins: 0
Liverpool vs Toulouse: Confirmed Toulouse lineup
19:07 , Jonathan Gorrie
Toulouse XI: Restes; Desler, Costa, Nicolaisen, Diarra, Suazo; Schmidt, Sierro, Casseres; Dallinga, Donnum Subs: Dominguez, Lacombe, Genreau, Cesar, Kamanzi, Mawissa, Begraoui, Magri, Bangre, Keben
Liverpool vs Toulouse: Confirmed Liverpool lineup
18:59 , Jonathan Gorrie
Liverpool XI: Kelleher; Alexander-Arnold, Gomez, Matip, Chambers; Endo, Jones, Gravenberch; Elliott, Nunez, JotaSubs: Alisson, Jaros, Van Dijk, Diaz, Mac Allister, Salah, Gakpo, Tskimikas, Scanlon, McConnell, Quansah, Szoboszlai
Liverpool vs Toulouse: Ibrahima Konate could have been sent off against Everton, Jurgen Klopp admits
18:16 , Jonathan Gorrie
Jurgen Klopp has admitted Ibrahima Konate "could have gone" after the Liverpool defender controversy escaped being sent off as Liverpool beat Everton on Saturday.
The Toffees saw Ashley Young handed two yellow cards in the first half and thought the numbers should have been levelled soon after the break when Konate tripped striker Beto when already on a booking.
Their appeals were dismissed by the referee, much to their disbelief, and Klopp has accepted the decision was likely incorrect.
He told TNT Sport: "I liked a lot of moments and then the red card was pretty influential in the game. I wanted us to be calm and ignore that we were one man up. It is difficult in the stands because it’s like now you have to create with each possession and it took a while until we got chances.
"And then the penalty. I saw it back and it is a clear penalty. Ibrahima, could have gone, yes. It could have happened obviously and then we took him off and from that moment we were solid and compact."
Liverpool vs Toulouse: Latest odds
18:00 , Jonathan Gorrie
Liverpool - 1/7
Draw - 5/1
Toulouse - 11/1
Odds via Betfair.
Liverpool vs Toulouse: Jurgen Klopp hints at bigger role for Darwin Nunez
17:39 , Jonathan Gorrie
Jurgen Klopp has tipped Darwin Nunez to hit top gear for Liverpool ahead of the Europa League clash with Toulouse.
The Uruguayan striker was among the substitutes for the Merseyside derby win over Everton due to a minor injury as he looks to cement his place in the Reds' starting XI.
Despite being a club-record £85million buy in the summer of 2022, Nunez has started fewer than half of his club's league games and struggled for consistent form in front of goal.
However, Klopp is adamant that fans are about to see him reach his potential.
Prediction: Liverpool's firepower to prove too much
17:33 , Jonathan Gorrie
Liverpool have so much attacking power in their squad that it's difficult to imagine Toulouse being able to cope, even if there is heavy rotation from Klopp tonight.
Toulouse team news: Aboukhlal injured
17:32 , Jonathan Gorrie
For Toulouse, Zakaria Aboukhlal and Oliver Zanden are both injured and the game will likely come too soon for Ibrahim Cissoko. Stijn Spierings, however, is available after suspension along with Logan Costa.
Liverpool team news: Gakpo returns from injury
17:31 , Jonathan Gorrie
Andy Roberston is the headline absentee for Liverpool after undergoing shoulder surgery on an injury picked up during the international break.
Cody Gakpo, however, could return from his knee problem after missing the last three games now he is back in training.
Midfielders Thiago Alcantara and Stefan Bajcetic are both out, alongside youngster Ben Doak.
Where to watch Liverpool vs Toulouse
17:31 , Jonathan Gorrie
TV channel: Tonight's game will be broadcast live on TNT Sports 1 and TNT Sports Ultimate in the UK. Coverage starts at 7:45pm.
Live stream: Subscribers will also be able to watch the match online via a live stream on the TNT Sports website and Discovery+ app.
LIVE coverage: Follow all the action tonight with Standard Sport’s dedicated match blog.
17:26 , Jonathan Gorrie
Good evening and welcome to Standard Sport's LIVE coverage of Liverpool's Europa League meeting with Toulouse.
Kick-off at Anfield is at 8pm BST.