It wasn't the start Jurgen Klopp's Reds wanted as they bid to go one better in the 2022/23 title race than they did a season ago.
The Eagles failed to fully fly either with Arsenal getting the better of them on opening night at Selhurst Park.
Liverpool won both meetings of these two sides last season, securing a 3-0 win at Anfield before a 3-1 victory on the road.
Here's everything you need to know:
When is the match?
The match takes place on Monday 15 August with kick-off at Anfield at 8pm.
What TV channel is it on?
The game will be broadcast on Sky Sports Main Event and Sky Sports Premier League.
What's the team news?
Klopp hopes Thiago Alcantara’s absence with a hamstring problem will only be four weeks. The Spain midfielder was forced off in last weekend’s draw at Fulham and the initial prognosis could see him out until the potentially the end of September.
Joel Matip has a groin injury and will miss out while Ibrahima Konate remains sidelined too, paving the way for Joe Gomez to start alongside Virgil van Dijk in defence.
For the visitors, Michael Olise could be involved after injury, while James McArthur and James Tomkins remain out. Nathan Ferguson is also unavailable.
Liverpool: Alisson; Alexander-Arnold, Gomez, Van Dijk, Robertson; Henderson, Fabinho, Elliott; Diaz, Nunez, Salah
Crystal Palace: Guaita, Clyne, Andersen, Guehi, Mitchell, Doucoure, Schlupp, Eze, Ayew, Zaha, Edouard
They weren't themselves a week ago but the Reds still boast a formidable record at home and should be too strong for the Eagles here. Liverpool 3-0 Crystal Palace