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Jacksonville Jaguars at Tennessee Titans: Predictions, picks and odds for NFL Week 14 matchup

Derrick Henry and the Tennessee Titans (7-5) are running away with the AFC South, but can Trevor Lawrence's Jacksonville Jaguars (4-8) pull off an upset in Nashville?

Coach Doug Pederson's Jaguars are coming off a Week 13 loss and hoping to build some momentum through the end of the season. Meanwhile, Henry, Ryan Tannehill and Co. are looking to increase their seeding in the AFC playoff picture by winning as many games as possible down the stretch. The game kicks off Sunday at 1 p.m. ET from Nissan Stadium.

Here's a look at the betting details and USA TODAY's NFL staff picks for the Jaguars vs. Titans Week 14 game:

Jaguars at Titans odds, moneyline and over/under

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NFL Week 14 odds, predictions and picks

Raiders vs. Rams | Ravens vs. Steelers | Jaguars vs. Titans | Vikings vs. Lions | Texans vs. Cowboys | Jets vs. Bills | Eagles vs. Giants | Browns vs. Bengals | Chiefs vs. Broncos | Panthers vs. Seahawks | Buccaneers vs. 49ers | Dolphins vs. Chargers | Patriots vs. Cardinals

Lorenzo Reyes: Titans 25, Jaguars 15

Tennessee is coming off of a game in which it got completely handled and fired its general manager. Still, the Titans had been pretty solid plays prior to the last two weeks and I think this is a great bounce-back spot for them against an inconsistent Jaguars team that struggles to play complete games.

Jacksonville Jaguars quarterback Trevor Lawrence (16) is greeted by teammate running back James Robinson (25) as Lawrence left the field following Sunday's loss to the Titans. The Jacksonville Jaguars hosted the Houston Texans at TIAA Bank Field in Jacksonville, FL Sunday, October 9, 2022. The Jaguars fell to the Texans with a final score of 13 to 6. [Bob Self/Florida Times-Union]

Richard Morin: Titans 30, Jaguars 14

A banged-up Lawrence is the last thing the Jaguars need in a tough road game, and the Titans desperately need a win. I'll take Tennessee and the points.

Lance Pugmire: Titans 27, Jaguars 13

Jacksonville’s ability to keep games close was sabotaged by Detroit, while Tennessee is positioned to squelch its two-game losing skid and affirm its repeat AFC South title.

Jarrett Bell: Titans 21, Jaguars 13

Nate Davis: Titans 24, Jaguars 17

Tyler Dragon: Titans 24, Jaguars 21

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This article originally appeared on USA TODAY: Jacksonville Jaguars at Tennessee Titans: Game predictions, picks, odds