* MSCI Asia ex-Japan falls 2%, lowest since Nov. 2020
* Powell warns inflation above long-run goal
* Fed fund futures pricing in 5 hikes
* U.S. 2-year yield near 2-year highs
By Andrew Galbraith
SHANGHAI, Jan 27 (Reuters) - Asian shares plunged to their lowest in nearly 15 months, short-term U.S. yields hit 23-month highs and the dollar strengthened on Thursday after the Federal Reserve's chairman signalled plans to steadily tighten policy.
The share rout looked set to continue into European and U.S. trading. Pan-region Euro Stoxx 50 futures tumbled 2.88%, FTSE futures lost 1.98%, Nasdaq futures dropped 1.73% and S&P 500 e-minis shed 1.56%.
At the same time, rising investor concerns over political tensions between Russia and Ukraine exacerbated worries over tight energy market supply, keeping oil prices elevated at multi-year highs despite some profit-taking.
In its latest policy update on Wednesday, the Fed indicated it is likely to raise U.S. interest rates in March, as has been widely expected, and reaffirmed plans to end its bond purchases that month before launching a significant reduction in its asset holdings.
But in the follow-up press conference, Powell warned that inflation remains above the Fed's long-run goal and supply chain issues may be more persistent than previously thought.
"There was a marked shift in terms of a relatively dovish statement and then a relatively hawkish press conference," said David Chao, global market strategist, Asia Pacific (ex-Japan) at Invesco.
"Powell (is) not committing to the size or the frequency of rate hikes and also the timing of the balance sheet reduction. I think that buys him a bit of wiggle room as to how quickly and with what velocity he wants to normalise monetary policy in the U.S." said Chao, adding that moves would depend on upcoming economic data.
Fed funds futures showed traders pricing in as many as five hikes by December, after previously fully pricing for four increases.
Concerns that the Fed will increasingly prioritise fighting inflation walloped share markets. MSCI's broad gauge of regional markets outside Japan fell 2.2% on Thursday to its lowest level since Nov. 5, 2020, and is on track for its worst week since Feb. 2021.
Hong Kong's Hang Seng index fell 2.4%, Australian shares lost 1.77% and Chinese blue-chips dropped to their lowest level since Sept. 30, 2020 as Refinitiv flows data pointed to heavy selling by foreign investors through the country's Stock Connect scheme.
In Tokyo, the Nikkei fell more than 3%, touching its lowest point since Nov. 2020.
U.S. YIELDS JUMP
Expectations of Fed tightening sent the policy-sensitive U.S. 2-year yield to a top of 1.1920% in Asian trade, a level last reached in February 2020. The benchmark 10-year yield was steady at 1.8495% having hit a high of 1.88% on Wednesday.
These in turn helped the dollar, lifting the dollar index, which measures the greenback against major peers, to 96.604, near five-week highs..
The greenback rested against the yen on Thursday at 114.6 yen per dollar, having gained 0.67% the day before, while the euro was at a six-week low of $1.2301
"The interesting play seems to be that yield differentials matter again, so we've got a decent set-up on dollar-yen. If you look at the yield differential between the 2-year on the U.S. and the Japanese, it's just shot up," said Matt Simpson, senior market analyst at City Index in Sydney.
The spread between the U.S. and Japanese 2-year yield widened to 124.22 basis points on Thursday, its highest since late February 2020.
In commodities markets, oil prices eased but remained elevated near $90 per barrel, a level last seen in October 2014, on festering tensions between Russia and Ukraine.
The United States said on Wednesday it had set out a diplomatic path to address sweeping Russian demands in eastern Europe, as Moscow held security talks with Western countries and intensified its military build-up near Ukraine with new drills.
On Thursday, global benchmark Brent crude fell 0.8% on profit taking to $89.15 per barrel. U.S. West Texas Intermediate crude was down 0.94% at $86.53.
U.S. officials say they are in talks with major energy-producing countries and companies worldwide over a potential diversion of supplies to Europe if Russia invades Ukraine, although the White House said it faces challenges finding alternative sources of energy supplies.
Spot gold slipped 0.3% to $1,813 an ounce, having been as high as $1,853.6 earlier in the week.
"When you see gold falling with stocks it's usually a signal that things aren't so well, but you can really tie everything back to the Fed raising rates, the dollar screaming higher with the yields, everything else is going the opposite way," said Simpson at City Index.
(Reporting by Andrew Galbraith; additional reporting by Alun John in Hong Kong editing by Richard Pullin)