The band were scheduled to perform in Las Vegas on Saturday (3 December) at the Dolby Live venue.
Hours before they were due to come on stage, however, Aerosmith issued a statement stating that the show had been cancelled.
The statement said that frontman Tyler, 74, was “feeling unwell and unable to perform”.
“It is with great disappointment that we are forced to cancel tonight’s show in Las Vegas due to Steven feeling unwell and unable to perform,” they wrote.
They assured fans that Tyler is expected to make a full recovery for Monday night’s Las Vegas show (5 Decemeber).
“We sincerely apologise for the last minute choice,” they said.
Refunds will be made available to ticket-holders through their “point of purchase”.
The Boston-based rock band is behind hits such as “Dream On” (1973) and “I Don’t Want To Miss A Thing” (1998).
Disappointed fans reacted to the news on social media, many expressing their frustrations at the late-notice while others sent their well wishes to Tyler.
The frontman and former American Idol judge recently left rehab after he checked into a facility in May. There has been no suggestion that his current illness is drug-related.
He has previously spoken about his struggles with substance abuse, once revealing that his bandmates and management staged an intervention for him in 1988.
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